Protein: RORG
Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Nuclear receptor subfamily 1 group F member 3) (RAR-related orphan receptor C) (Retinoid-related orphan receptor-gamma)

Gene: RORG, RORC
Organism: Homo sapiens
Interactions: 47
UniProt ID: P51449

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

902780

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

17

High-throughput

0.656

High

902772

PRS8
26S proteasome regulatory subunit 8

3

19

High-throughput

0.654

High

902782

NCOA1
Nuclear receptor coactivator 1

1

20

Small-scale

0.647

High

902784

Q58EY0
RAR related orphan receptor B isoform 1

1

17

High-throughput

0.621

High

902797

NCOA3
Nuclear receptor coactivator 3

1

20

Small-scale

0.618

High

902787

RORB
Nuclear receptor ROR-beta

1

16

High-throughput

0.590

High

902785

ANKH1
Ankyrin repeat and KH domain-containing protein 1

2

3

High-throughput

0.558

High

132708

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

20

High-throughput

0.552

High

192906

CLOCK
Circadian locomoter output cycles protein kaput

1

20

High-throughput

0.552

High

413438

P53
Cellular tumor antigen p53

1

4

High-throughput

0.536

High

717726

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

3

High-throughput

0.508

High

718087

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

3

High-throughput

0.508

High

786456

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

6

High-throughput

0.508

High

902770

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

6

High-throughput

0.508

High

902771

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

6

High-throughput

0.508

High

902773

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

5

High-throughput

0.508

High

902779

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

1

High-throughput

0.508

High

902783

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

1

High-throughput

0.508

High

902786

BMAL2
Basic helix-loop-helix ARNT-like protein 2

1

20

High-throughput

0.508

High

902789

NPAS2
Neuronal PAS domain-containing protein 2

1

20

High-throughput

0.508

High

902788

CBP
CREB-binding protein

1

20

Small-scale

0.501

High

902795

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

16

Small-scale

0.501

High

176168

PER2
Period circadian protein homolog 2

1

20

High-throughput

0.481

High

885726

KC1E
Casein kinase I isoform epsilon

1

9

High-throughput

0.481

High

902778

NCOA6
Nuclear receptor coactivator 6

1

20

High-throughput

0.481

High

902792

BHE41
Class E basic helix-loop-helix protein 41

1

20

High-throughput

0.481

High

136672

TRAF5
TNF receptor-associated factor 5

1

13

Small-scale

0.479

High

322916

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

5

Small-scale

0.479

High

557182

SRC
Proto-oncogene tyrosine-protein kinase Src

1

13

Small-scale

0.479

High

608506

DDX5
Probable ATP-dependent RNA helicase DDX5

1

11

Small-scale

0.479

High

902774

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

902775

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

Small-scale

0.479

High

902776

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

902777

CUL4B
Cullin-4B

1

11

Small-scale

0.479

High

902781

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

902790

FOXP3
Forkhead box protein P3

1

20

Small-scale

0.479

High

902796

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

Small-scale

0.479

High

902793

FXL15
F-box/LRR-repeat protein 15

1

2

High-throughput

0.464

High

902791

CIPC
CLOCK-interacting pacemaker

1

0

High-throughput

0.460

High

154950

BHE40
Class E basic helix-loop-helix protein 40

1

19

High-throughput

0.457

High

429548

JUN
Transcription factor Jun

1

14

High-throughput

0.445

High

902794

DEC1
Deleted in esophageal cancer 1

1

2

High-throughput

0.439

High

96874

E9PDP5
Ankyrin repeat and KH domain containing 1

1

3

High-throughput

0.407

High

593649

BGAL
Beta-galactosidase

2

0

High-throughput

0.328

High

652838

EVI2A
Protein EVI2A

1

0

High-throughput

0.282

High

351753

SG1D2
Secretoglobin family 1D member 2

1

0

High-throughput

0.279

Low

528667

PPGB
Lysosomal protective protein

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025