HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: AJUBA (Q96IF1)
LIM domain-containing protein ajuba
Gene: AJUBA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15870274
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005911 - cell-cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 509 Hs			1 538
+	Hs
		439995 LCK_HUMAN (1-509): 0: 655: 100.00		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		473382 HCK_HUMAN (1-509): 0: 599: 65.04		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		440442 FYN_HUMAN (1-507): 0: 587: 54.19		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		557175 SRC_HUMAN (20-507): 0: 585: 55.00		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		463403 LYN_HUMAN (1-509): 0: 581: 62.72		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		463023 YES_HUMAN (26-507): 0: 580: 58.06		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		878418 BLK_HUMAN (1-509): 0: 553: 59.35		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		473416 HCK_HUMAN (1-509): 0: 599: 65.04		FHL2_HUMAN (364-537): 4.17e-35: 134: 22.16
+	Hs
		270702 SRC_HUMAN (20-507): 0: 585: 55.00		LDB3_HUMAN (16-537): 1.31e-27: 119: 14.61
+	Mm
		431364 SRC_MOUSE (21-507): 0: 582: 56.24		PAXI_MOUSE (10-459): 1.34e-28: 121: 18.10
+	Hs
		362210 ABL1_HUMAN (34-502): 6.9e-173: 518: 41.09		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		840935 ABL2_HUMAN (21-502): 8.49e-172: 517: 40.20		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		473426 HCK_HUMAN (1-509): 0: 599: 65.04		TRIP6_HUMAN (100-536): 3.93e-17: 85.9: 15.23
+	Hs
		840868 TEC_HUMAN (7-503): 1.91e-168: 491: 32.36		PAXI_HUMAN (10-528): 3.08e-50: 183: 15.77
+	Hs
		557321 SRC_HUMAN (20-507): 0: 585: 55.00		TRIP6_HUMAN (100-536): 3.93e-17: 85.9: 15.23
+	Hs
		117131 J3QRU1_HUMAN (26-507): 0: 580: 58.06		PDLI7_HUMAN (11-390): 1.11e-16: 84.7: 14.32
+	Hs
		463235 YES_HUMAN (26-507): 0: 580: 58.06		PDLI7_HUMAN (11-390): 1.11e-16: 84.7: 14.32
+	Ce
		113230 SRC2_CAEEL (1-507): 0: 526: 45.44		G5EFG1_CAEEL (19-454): 4.95e-26: 114: 13.51
+	Mm
		362452 ABL1_MOUSE (34-502): 4.64e-173: 519: 41.09		PAXI_MOUSE (10-459): 1.34e-28: 121: 18.10
+	Ce
		112295 SRC1_CAEEL (1-508): 0: 519: 44.84		G5EFG1_CAEEL (19-454): 4.95e-26: 114: 13.51