HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 225 Hs			1 305
+	Hs
		441287 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		SART3_HUMAN (2-302): 1.67e-38: 146: 16.32
+	Hs
		446637 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		SART3_HUMAN (2-302): 1.67e-38: 146: 16.32
+	Hs
		441393 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		441401 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		RBM8A_HUMAN (95-239): 7.02e-31: 115: 21.38
+	Hs
		446642 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RNPS1_HUMAN (1-234): 2e-34: 128: 100.00
+	Sc
		960476 NAM8_YEAST (1-224): 5.12e-42: 150: 16.09		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		446841 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		PPIE_HUMAN (159-297): 4.41e-33: 125: 17.73
+	Hs
		198830 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		446860 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RBM8A_HUMAN (95-239): 7.02e-31: 115: 21.38
+	Hs
		446547 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06
+	Hs
		446592 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		TIAR_HUMAN (155-250): 1.9e-18: 86.5: 27.08
+	Hs
		446516 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		TIA1_HUMAN (156-251): 3.47e-18: 85.7: 27.08
+	Sc
		775728 MSL1_YEAST (7-91): 8.04e-27: 100: 30.59		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		198843 PTBP1_HUMAN (5-224): 4.18e-17: 81.2: 16.07		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		198880 ELAV2_HUMAN (128-224): 1.33e-15: 76.3: 19.61		RFOX2_HUMAN (44-274): 2.32e-31: 122: 13.25
+	Hs
		643457 PTBP1_HUMAN (5-224): 4.18e-17: 81.2: 16.07		NCBP2_HUMAN (128-271): 1.08e-30: 114: 18.06
+	Mm
		665745 TIA1_MOUSE (2-160): 4.64e-17: 80.5: 14.29		PABP1_MOUSE (65-252): 1.7e-21: 96.5: 16.32
+	Hs
		680439 TIA1_HUMAN (2-160): 1.14e-16: 79.4: 13.04		TIAR_HUMAN (155-250): 1.9e-18: 86.5: 27.08
+	Hs
		680422 TIA1_HUMAN (2-160): 1.14e-16: 79.4: 13.04		TIA1_HUMAN (156-251): 3.47e-18: 85.7: 27.08
+	Hs
		474019 ELAV2_HUMAN (128-224): 1.33e-15: 76.3: 19.61		PAB4L_HUMAN (161-242): 1.56e-18: 86.5: 30.49