HitPredict

Interactor 1: GELS (P06396)
Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin)
Gene: GSN

Interactor 2: PKHG6 (Q3KR16)
Pleckstrin homology domain-containing family G member 6 (PH domain-containing family G member 6) (Myosin-interacting guanine nucleotide exchange factor) (MyoGEF)
Gene: PLEKHG6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 782 Hs			1 790
+	Hs
		442448 GELS_HUMAN (1-782): 0: 1207: 100.00		FGD4_HUMAN (59-692): 1.43e-99: 327: 14.92
+	Hs
		442350 GELS_HUMAN (1-782): 0: 1207: 100.00		Q5JYA6_HUMAN (45-746): 6.78e-87: 302: 15.93
+	Hs
		442375 GELS_HUMAN (1-782): 0: 1207: 100.00		PKHG7_HUMAN (142-513): 3.11e-91: 302: 24.64
+	Hs
		442523 GELS_HUMAN (1-782): 0: 1207: 100.00		PKHG1_HUMAN (45-746): 6.78e-87: 302: 15.93
+	Hs
		442479 GELS_HUMAN (1-782): 0: 1207: 100.00		ECT2_HUMAN (77-645): 5.33e-81: 280: 19.26
+	Hs
		1093315 FLII_HUMAN (373-765): 2.37e-57: 214: 22.88		ECT2_HUMAN (77-645): 5.33e-81: 280: 19.26
+	Hs
		336488 SVIL_HUMAN (551-779): 2.12e-24: 112: 21.86		ECT2_HUMAN (77-645): 5.33e-81: 280: 19.26