HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: GEMI5 (Q8TEQ6)
Gem-associated protein 5 (Gemin5)
Gene: GEMIN5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26496610, 28514442, 29802200, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0030619 - U1 snRNA binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 1508
+	Hs
		516438 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		WDR5_HUMAN (2-137): 6.26e-21: 97.9: 15.22
+	Hs
		516740 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		FZR1_HUMAN (236-500): 7.61e-13: 74.8: 20.90
+	Dm
		1129076 SET1_DROME (53-387): 1.25e-41: 160: 20.59		WDS_DROME (2-141): 1.85e-22: 102: 15.49
+	Hs
		442587 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		FZR1_HUMAN (236-500): 7.61e-13: 74.8: 20.90
+	Hs
		903196 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		WDR5_HUMAN (2-137): 6.26e-21: 97.9: 15.22
+	Hs
		1357231 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		FZR1_HUMAN (236-500): 7.61e-13: 74.8: 20.90
+	Hs
		1031495 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		FZR1_HUMAN (236-500): 7.61e-13: 74.8: 20.90
+	Hs
		235781 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		WDR5_HUMAN (2-137): 6.26e-21: 97.9: 15.22
+	Hs
		236130 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		FZR1_HUMAN (236-500): 7.61e-13: 74.8: 20.90