HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: JUND (P17535)
Transcription factor JunD (Transcription factor AP-1 subunit JunD)
Gene: JUND

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 347
+	Hs
		482828 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		JUND_HUMAN (1-347): 5.97e-75: 236: 100.00
+	Hs
		429152 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		JUN_HUMAN (1-347): 2.01e-67: 216: 49.17
+	Hs
		429177 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		JUN_HUMAN (1-347): 2.01e-67: 216: 49.17
+	Mm
		432073 TPM1_MOUSE (2-285): 1.15e-44: 154: 91.55		JUN_MOUSE (1-347): 3.4e-67: 216: 49.59
+	Hs
		447665 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		JUNB_HUMAN (1-347): 2.64e-64: 209: 38.65
+	Mm
		432074 TPM2_MOUSE (2-285): 2.22e-40: 143: 86.62		JUN_MOUSE (1-347): 3.4e-67: 216: 49.59
+	Hs
		3293 A0A0S2Z4G4_HUMAN (44-285): 1.76e-36: 132: 72.31		JUN_HUMAN (1-347): 2.01e-67: 216: 49.17
+	Hs
		447660 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		ATF2_HUMAN (22-347): 4.97e-47: 167: 19.82
+	Hs
		482827 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		ATF2_HUMAN (22-347): 4.97e-47: 167: 19.82
+	Hs
		583527 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		ATF2_HUMAN (22-347): 4.97e-47: 167: 19.82
+	Dm
		447911 TPM1_DROME (44-282): 3.15e-32: 123: 55.23		JRA_DROME (1-340): 1.4e-44: 156: 29.65
+	Hs
		617146 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		ATF3_HUMAN (190-334): 2.05e-13: 69.8: 20.13