HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: CC146 (Q8IYE0)
Coiled-coil domain-containing protein 146
Gene: CCDC146

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25416956
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 955
+	Hs
		1218089 Q5VU62_HUMAN (128-285): 1.67e-39: 137: 100.00		CC146_HUMAN (1-955): 3.09e-81: 285: 100.00
+	Dm
		447919 TPM1_DROME (44-282): 3.15e-32: 123: 55.23		Q59E59_DROME (223-955): 2.61e-37: 154: 10.64
+	Mm
		107190 LAMA1_MOUSE (4-280): 3.28e-51: 182: 14.84		F8VQJ3_MOUSE (63-417): 5.23e-10: 65.7: 11.81
+	Hs
		447692 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		MYH9_HUMAN (545-955): 3.11e-18: 92.8: 12.80
+	Hs
		482842 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		MYH9_HUMAN (545-955): 3.11e-18: 92.8: 12.80
+	Hs
		156848 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		CTRO_HUMAN (278-871): 3.2e-17: 89.7: 12.52
+	Dm
		432162 TPM2_DROME (2-284): 1.25e-36: 133: 47.70		MYSA_DROME (378-954): 1.29e-23: 110: 10.26
+	Hs
		464124 TPM2_HUMAN (2-285): 1.41e-40: 143: 86.27		MYH9_HUMAN (545-955): 3.11e-18: 92.8: 12.80
+	Hs
		116462 H7BYY1_HUMAN (41-285): 5.71e-36: 130: 64.90		MYH9_HUMAN (545-955): 3.11e-18: 92.8: 12.80
+	Hs
		772732 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		MYH9_HUMAN (545-955): 3.11e-18: 92.8: 12.80
+	Hs
		447819 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		MY18A_HUMAN (362-872): 3.45e-09: 63.4: 13.67
+	Hs
		482942 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		MY18A_HUMAN (362-872): 3.45e-09: 63.4: 13.67
+	Hs
		157221 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		CTRO_HUMAN (278-871): 3.2e-17: 89.7: 12.52
+	Dm
		447927 TPM1_DROME (44-282): 3.15e-32: 123: 55.23		MYSN_DROME (423-919): 3.57e-16: 85.9: 9.88
+	Hs
		464191 TPM2_HUMAN (2-285): 1.41e-40: 143: 86.27		MY18A_HUMAN (362-872): 3.45e-09: 63.4: 13.67
+	Hs
		116468 H7BYY1_HUMAN (41-285): 5.71e-36: 130: 64.90		MY18A_HUMAN (362-872): 3.45e-09: 63.4: 13.67
+	Hs
		995453 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		MY18A_HUMAN (362-872): 3.45e-09: 63.4: 13.67
+	Mm
		384328 LAMB1_MOUSE (3-211): 3.01e-16: 80.8: 19.05		LAMC1_MOUSE (63-417): 2.63e-10: 66.8: 11.81