Interactor 1: MMP7 (P09237)
Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase)
Gene: MMP7
Interactor 2: DEF1 (P59665)
Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)]
Gene: DEFA1
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 0.60 | 0.501 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19181662 |
| Identification Methods | protease assay |
| Interaction Type | cleavage reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0050829 - defense response to Gram-negative bacterium GO:0050830 - defense response to Gram-positive bacterium GO:0070062 - extracellular exosome |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
