HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: HNRPU (Q00839)
Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120)
Gene: HNRNPU

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.648

The method score is based on:

Property Details
Experiments 29721183, 31694235
Identification Methods affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003690 - double-stranded DNA binding
GO:0003697 - single-stranded DNA binding
GO:0003714 - transcription corepressor activity
GO:0003723 - RNA binding
and 4 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 215
Hs

1 825
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024