HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: GOGA2 (Q08379)
Golgin subfamily A member 2 (130 kDa cis-Golgi matrix protein) (GM130) (GM130 autoantigen) (Golgin-95)
Gene: GOLGA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.597

Property	Details
Experiments	25416956, 25910212
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid bait and prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 1002
+	Dm
		419108 TPM1_DROME (1-281): 3.07e-56: 186: 44.78		MYSN_DROME (453-976): 4.74e-18: 92.1: 10.09
+	Hs
		451293 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		419011 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		434415 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		451201 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		418895 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		110802 H7BYY1_HUMAN (41-284): 8.14e-35: 127: 70.49		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		932031 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		MY18A_HUMAN (356-887): 3.84e-17: 89.4: 15.82
+	Hs
		434354 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Dm
		404216 TPM2_DROME (1-282): 7.75e-35: 128: 49.29		MYSA_DROME (529-981): 3.7e-14: 79.4: 11.78
+	Hs
		110796 H7BYY1_HUMAN (41-284): 8.14e-35: 127: 70.49		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87
+	Hs
		724765 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		MYH9_HUMAN (12-375): 3.45e-11: 69.7: 9.87