Interactor 1: GCH1 (P0A6T5)
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)
Gene: folE

Interactor 2: GCH1 (P0A6T5)
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)
Gene: folE

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.755

The method score is based on:

Property Details
Experiments 11087827, 7663943
Identification Methods x-ray crystallography
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains GTP_cyclohydroI~GTP_cyclohydroI
Common GO terms GO:0003934 - GTP cyclohydrolase I activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006729 - tetrahydrobiopterin biosynthetic process
and 5 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 222
Ec

1 222
+ Rn
+ Hs
+ Ce
+ Sc
+ Dm
+ Hp
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024