Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1
Interactor 2: VASP (P50552)
Vasodilator-stimulated phosphoprotein (VASP)
Gene: VASP
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.80 | 0.60 | 0.697 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10882740, 34079125, 35271311, 32814053 |
| Identification Methods | two hybrid, affinity chromatography technology, proximity labelling technology, luminescence based mammalian interactome mapping, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001843 - neural tube closure GO:0003779 - actin binding GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0030838 - positive regulation of actin filament polymerization and 3 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
