HitPredict

Interactor 1: HNRPC (P07910)
Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene: HNRNPC

Interactor 2: RA1L2 (Q32P51)
Heterogeneous nuclear ribonucleoprotein A1-like 2 (hnRNP A1-like 2) (hnRNP core protein A1-like 2)
Gene: HNRNPA1L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 306 Hs			1 320
+	Hs
		462591 HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00		ROAA_HUMAN (3-276): 1.34e-67: 216: 34.75
+	Hs
		171989 HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00		HNRDL_HUMAN (2-292): 1.63e-55: 187: 33.11
+	Hs
		462207 HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00		ROA1_HUMAN (1-188): 1.66e-53: 181: 97.34
+	Hs
		74431 HNRC2_HUMAN (1-306): 3.31e-80: 246: 84.64		ROA1_HUMAN (1-188): 1.66e-53: 181: 97.34
+	Hs
		462220 HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00		PABP1_HUMAN (1-193): 5.19e-42: 155: 18.56
+	Hs
		172247 RALY_HUMAN (2-298): 3.9e-63: 203: 39.87		HNRDL_HUMAN (2-292): 1.63e-55: 187: 33.11
+	Hs
		485501 RALY_HUMAN (2-298): 3.9e-63: 203: 39.87		ROA1_HUMAN (1-188): 1.66e-53: 181: 97.34
+	Mm
		710990 RALY_MOUSE (3-300): 1.06e-66: 212: 42.19		PABP1_MOUSE (1-193): 5.73e-42: 155: 18.56
+	Hs
		550512 RALY_HUMAN (2-298): 3.9e-63: 203: 39.87		PABP1_HUMAN (1-193): 5.19e-42: 155: 18.56
+	Hs
		462312 HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00		ROA3_HUMAN (96-192): 7.01e-21: 93.6: 26.80
+	Hs
		214261 HNRC1_HUMAN (1-306): 2.49e-87: 264: 86.93		MSI1H_HUMAN (3-107): 3.12e-17: 83.2: 34.29
+	Hs
		256623 HNRC1_HUMAN (1-306): 2.49e-87: 264: 86.93		HNRPD_HUMAN (3-101): 5.99e-17: 82.4: 31.31
+	Hs
		462382 HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00		ROA0_HUMAN (4-94): 4.65e-20: 90.5: 36.26
+	Hs
		462403 HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00		HNRPD_HUMAN (3-101): 5.99e-17: 82.4: 31.31
+	Hs
		462242 HNRPC_HUMAN (1-306): 1.27e-83: 255: 100.00		ROA2_HUMAN (3-97): 2.32e-15: 77.8: 31.58
+	Hs
		485275 RB15B_HUMAN (9-292): 7.12e-31: 124: 12.03		ROA1_HUMAN (1-188): 1.66e-53: 181: 97.34
+	Hs
		485046 TRA2B_HUMAN (4-164): 1.15e-27: 110: 21.77		ROA1_HUMAN (1-188): 1.66e-53: 181: 97.34
+	Hs
		650832 RALYL_HUMAN (3-284): 4.2e-66: 210: 52.23		ROA2_HUMAN (3-97): 2.32e-15: 77.8: 31.58
+	Hs
		1120385 RALY_HUMAN (2-298): 3.9e-63: 203: 39.87		HNRPD_HUMAN (3-101): 5.99e-17: 82.4: 31.31
+	Hs
		550217 TRA2B_HUMAN (4-164): 1.15e-27: 110: 21.77		PABP1_HUMAN (1-193): 5.19e-42: 155: 18.56