HitPredict

Interactor 1: TPM2 (P07951)
Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2)
Gene: TPM2

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 327
+	Hs
		482874 TPM1_HUMAN (1-284): 1.74e-45: 156: 85.56		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		447731 TPM3_HUMAN (1-284): 5.74e-44: 152: 86.27		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		447696 TPM3_HUMAN (1-284): 5.74e-44: 152: 86.27		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Dm
		482737 TPM2_DROME (1-282): 5.04e-36: 131: 47.52		PP1B_DROME (1-322): 0: 568: 90.37
+	Dm
		447917 TPM1_DROME (4-281): 6.86e-30: 116: 43.79		PP1B_DROME (1-322): 0: 568: 90.37
+	Hs
		116465 H7BYY1_HUMAN (1-234): 3.56e-15: 75.3: 22.22		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		968246 TPM4_HUMAN (1-240): 7.77e-14: 71.4: 21.67		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		786531 TPM4_HUMAN (1-240): 7.77e-14: 71.4: 21.67		PP1G_HUMAN (1-327): 0: 569: 86.89