HitPredict

Interactor 1: H7BYY1 (H7BYY1)
Tropomyosin 1
Gene: TPM1

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 327
+	Hs
		482874 TPM1_HUMAN (6-248): 1.35e-49: 165: 70.78		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		968246 TPM4_HUMAN (1-248): 5.57e-49: 163: 77.82		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		447731 TPM3_HUMAN (6-248): 5.42e-48: 161: 65.43		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		464139 TPM2_HUMAN (5-248): 6.69e-43: 148: 63.53		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		786531 TPM4_HUMAN (1-248): 5.57e-49: 163: 77.82		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		447696 TPM3_HUMAN (6-248): 5.42e-48: 161: 65.43		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Dm
		447917 TPM1_DROME (5-245): 1.09e-43: 152: 48.96		PP1B_DROME (1-322): 0: 568: 90.37
+	Dm
		482737 TPM2_DROME (5-246): 1.31e-39: 140: 41.32		PP1B_DROME (1-322): 0: 568: 90.37