HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 327
+	Hs
		482874 TPM1_HUMAN (2-285): 1.36e-44: 154: 91.20		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		464139 TPM2_HUMAN (2-285): 1.41e-40: 143: 86.27		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		116465 H7BYY1_HUMAN (41-285): 5.71e-36: 130: 64.90		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		447696 TPM3_HUMAN (1-285): 1.29e-44: 154: 100.00		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		968246 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Dm
		482737 TPM2_DROME (2-284): 1.25e-36: 133: 47.70		PP1B_DROME (1-322): 0: 568: 90.37
+	Hs
		786531 TPM4_HUMAN (43-285): 3.76e-34: 126: 69.96		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		967788 FKB15_HUMAN (1-284): 9.48e-29: 117: 13.40		PP1A_HUMAN (1-326): 0: 576: 88.79
+	Dm
		447917 TPM1_DROME (44-282): 3.15e-32: 123: 55.23		PP1B_DROME (1-322): 0: 568: 90.37