HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: SC6A8 (P48029)
Sodium- and chloride-dependent creatine transporter 1 (CT1) (Creatine transporter 1) (Solute carrier family 6 member 8)
Gene: SLC6A8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 635
+	Hs
		869574 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		SC6A8_HUMAN (1-621): 0: 756: 100.00
+	Hs
		869579 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		SC6A8_HUMAN (1-621): 0: 756: 100.00
+	Hs
		869581 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		SC6A8_HUMAN (1-621): 0: 756: 100.00
+	Hs
		869572 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		SC6A8_HUMAN (1-621): 0: 756: 100.00
+	Hs
		580924 RAC2_HUMAN (1-193): 2.92e-77: 231: 54.12		SC6A8_HUMAN (1-621): 0: 756: 100.00
+	Hs
		869571 RAC3_HUMAN (1-179): 7.81e-75: 225: 57.54		SC6A8_HUMAN (1-621): 0: 756: 100.00
+	Hs
		727527 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		SC6A6_HUMAN (22-635): 0: 696: 53.82
+	Hs
		727528 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		SC6A6_HUMAN (22-635): 0: 696: 53.82
+	Hs
		727524 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		SC6A6_HUMAN (22-635): 0: 696: 53.82
+	Hs
		580889 RAC2_HUMAN (1-193): 2.92e-77: 231: 54.12		SC6A6_HUMAN (22-635): 0: 696: 53.82
+	Hs
		870441 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		SC6A9_HUMAN (41-624): 0: 682: 42.42
+	Hs
		870219 RAC3_HUMAN (1-179): 7.81e-75: 225: 57.54		S6A12_HUMAN (20-598): 0: 694: 54.47
+	Mm
		953803 CDC42_MOUSE (1-193): 8.86e-78: 232: 51.30		SC6A4_MOUSE (7-597): 0: 662: 41.25
+	Hs
		962468 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		S6A15_HUMAN (360-579): 1.15e-57: 209: 32.04
+	Hs
		988697 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		S6A15_HUMAN (360-579): 1.15e-57: 209: 32.04
+	Hs
		466454 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		S6A15_HUMAN (360-579): 1.15e-57: 209: 32.04
+	Hs
		1015774 RHOG_HUMAN (1-193): 2.26e-78: 233: 54.92		S6A15_HUMAN (360-579): 1.15e-57: 209: 32.04
+	Hs
		955579 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		S6A15_HUMAN (360-579): 1.15e-57: 209: 32.04
+	Hs
		581281 RAC2_HUMAN (1-193): 2.92e-77: 231: 54.12		S6A15_HUMAN (360-579): 1.15e-57: 209: 32.04
+	Hs
		953666 RAC3_HUMAN (1-179): 7.81e-75: 225: 57.54		S6A15_HUMAN (360-579): 1.15e-57: 209: 32.04