Interactor 1: BCCP (P0ABD8)
Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP)
Gene: accB

Interactor 2: ACCC (P24182)
Biotin carboxylase (EC 6.3.4.14) (Acetyl-coenzyme A carboxylase biotin carboxylase subunit A)
Gene: ACCC

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 16606699, 24561554, 23499019, 15690043
Identification Methods affinity chromatography technology, two hybrid, pull down, molecular sieving, x-ray crystallography, tandem affinity purification, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Biotin_carb_C~Biotin_lipoyl, Biotin_carb_N~Biotin_lipoyl, Biotin_lipoyl~CPSase_L_D2
Common GO terms GO:0003989 - acetyl-CoA carboxylase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006633 - fatty acid biosynthetic process
GO:0009317 - acetyl-CoA carboxylase complex
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 156
Ec

1 449
+ Ss
+ At
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024