HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: PAR3L (Q8TEW8)
Partitioning defective 3 homolog B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein) (PAR3-beta) (Partitioning defective 3-like protein) (PAR3-L protein)
Gene: PARD3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 1205
+	Hs
		962308 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PAR3L_HUMAN (1-1205): 0: 685: 100.00
+	Hs
		962307 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PARD3_HUMAN (1-1180): 6.42e-123: 414: 35.12
+	Hs
		988553 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		PARD3_HUMAN (1-1180): 6.42e-123: 414: 35.12
+	Hs
		466378 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		PARD3_HUMAN (1-1180): 6.42e-123: 414: 35.12
+	Hs
		961999 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		DLG1_HUMAN (47-742): 1.47e-49: 192: 10.71
+	Hs
		988325 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		DLG1_HUMAN (47-742): 1.47e-49: 192: 10.71
+	Mm
		988891 RAC1_MOUSE (1-193): 6.84e-81: 240: 57.22		DLG4_MOUSE (333-960): 4.68e-50: 192: 15.36
+	Hs
		466228 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		DLG1_HUMAN (47-742): 1.47e-49: 192: 10.71
+	Hs
		466372 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		LNX1_HUMAN (289-749): 7.23e-31: 132: 14.89
+	Hs
		962401 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		MAGI1_HUMAN (156-1191): 1.78e-23: 110: 11.86
+	Hs
		988627 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		MAGI1_HUMAN (156-1191): 1.78e-23: 110: 11.86
+	Hs
		962343 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		DLG3_HUMAN (47-389): 2.17e-21: 102: 12.83
+	Hs
		962291 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		INADL_HUMAN (264-937): 5.57e-15: 82.7: 10.92
+	Hs
		961996 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTN13_HUMAN (141-313): 9.3e-13: 75.4: 16.95
+	Hs
		988322 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		PTN13_HUMAN (141-313): 9.3e-13: 75.4: 16.95
+	Hs
		466227 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		PTN13_HUMAN (141-313): 9.3e-13: 75.4: 16.95
+	Dm
		828001 RAC1_DROME (1-193): 2.07e-78: 233: 54.12		SCRIB_DROME (504-689): 9.78e-14: 78.5: 18.52
+	Hs
		962039 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		SCRIB_HUMAN (123-285): 3.84e-09: 63.5: 15.48
+	Hs
		988360 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		SCRIB_HUMAN (123-285): 3.84e-09: 63.5: 15.48
+	Hs
		466247 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		SCRIB_HUMAN (123-285): 3.84e-09: 63.5: 15.48