HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 2517
+	Hs
		461838 HS90A_HUMAN (1-724): 0: 1069: 85.25		CIC_HUMAN (1-2517): 0: 945: 100.00
+	Hs
		468168 HS90B_HUMAN (1-724): 0: 1083: 100.00		SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05
+	Hs
		461262 HS90A_HUMAN (1-724): 0: 1069: 85.25		SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05
+	Hs
		461114 HS90A_HUMAN (1-724): 0: 1069: 85.25		MUC1_HUMAN (290-1100): 2.26e-47: 189: 13.89
+	Hs
		468651 HS90B_HUMAN (1-724): 0: 1083: 100.00		BBX_HUMAN (1078-1189): 1.69e-34: 147: 48.21
+	Hs
		461764 HS90A_HUMAN (1-724): 0: 1069: 85.25		BBX_HUMAN (1078-1189): 1.69e-34: 147: 48.21
+	Hs
		468721 HS90B_HUMAN (1-724): 0: 1083: 100.00		MINT_HUMAN (301-1665): 2.41e-21: 105: 10.27
+	Hs
		468609 HS90B_HUMAN (1-724): 0: 1083: 100.00		KMT2C_HUMAN (1133-2516): 1.63e-13: 79.5: 8.66
+	Hs
		462081 HS90A_HUMAN (1-724): 0: 1069: 85.25		PRC2C_HUMAN (367-2516): 2.74e-14: 81.8: 8.95
+	Hs
		468274 HS90B_HUMAN (1-724): 0: 1083: 100.00		ANK2_HUMAN (535-2223): 9.82e-09: 63.4: 10.19
+	Hs
		461766 HS90A_HUMAN (1-724): 0: 1069: 85.25		TITIN_HUMAN (750-1458): 4.36e-09: 64.6: 9.03