HitPredict

Interactor 1: PTPRQ (P0C5E4)
Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48)
Gene: PTPRQ

Interactor 2: DSG1A (Q61495)
Desmoglein-1-alpha (Desmoglein-1) (Dsg1-alpha) (DG1) (DGI) (Desmosomal glycoprotein I)
Gene: DSG1A

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16973135
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016324 - apical plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2300 Mm			1 1057
+	Mm
		472763 PTPRQ_MOUSE (1-2300): 0: 1552: 100.00		CADH5_MOUSE (4-484): 4.6e-87: 299: 18.84
+	Mm
		454937 PTPRQ_MOUSE (1-2300): 0: 1552: 100.00		CADH1_MOUSE (1-485): 3.32e-54: 206: 17.93
+	Mm
		472760 PTPRQ_MOUSE (1-2300): 0: 1552: 100.00		CADH2_MOUSE (1-300): 2.09e-37: 154: 21.61
+	Hs
		1031982 PTPRS_HUMAN (54-1029): 1.6e-80: 298: 16.67		DSG2_HUMAN (7-1056): 0: 790: 33.51
+	Hs
		1048596 PTPRO_HUMAN (1975-2257): 1.54e-73: 273: 47.02		DSG2_HUMAN (7-1056): 0: 790: 33.51
+	Hs
		1048635 PTPRU_HUMAN (17-191): 1.5e-16: 88.9: 15.30		DSG2_HUMAN (7-1056): 0: 790: 33.51
+	Hs
		616974 PTPRD_HUMAN (2-240): 4.16e-19: 97.4: 19.59		DSC3_HUMAN (4-780): 0: 647: 26.12
+	Hs
		489891 PTPRF_HUMAN (8-1003): 1.12e-99: 360: 18.17		CADH1_HUMAN (1-485): 5.32e-63: 233: 19.21
+	Hs
		521907 PTPRS_HUMAN (54-1029): 1.6e-80: 298: 16.67		CADH1_HUMAN (1-485): 5.32e-63: 233: 19.21
+	Rn
		1145482 PTPRF_RAT (8-984): 2.51e-100: 362: 17.99		CADH2_RAT (1-371): 7.94e-38: 155: 19.70
+	Hs
		580238 PTPRO_HUMAN (1975-2257): 1.54e-73: 273: 47.02		CADH2_HUMAN (1-371): 1.8e-37: 154: 18.77
+	Hs
		702788 PTPRU_HUMAN (17-191): 1.5e-16: 88.9: 15.30		CADH5_HUMAN (4-484): 9.11e-89: 304: 20.08
+	Hs
		521728 PTPRG_HUMAN (1973-2270): 5.52e-25: 116: 31.19		CADH1_HUMAN (1-485): 5.32e-63: 233: 19.21
+	Hs
		521898 PTPRJ_HUMAN (5-469): 3.79e-23: 110: 14.40		CADH1_HUMAN (1-485): 5.32e-63: 233: 19.21
+	Hs
		576981 PTPRA_HUMAN (1998-2257): 1.51e-45: 181: 37.50		CADH2_HUMAN (1-371): 1.8e-37: 154: 18.77
+	Hs
		521727 PTPRD_HUMAN (2-240): 4.16e-19: 97.4: 19.59		CADH1_HUMAN (1-485): 5.32e-63: 233: 19.21
+	Hs
		441173 PTPRC_HUMAN (2004-2267): 3.54e-32: 140: 30.17		CADH2_HUMAN (1-371): 1.8e-37: 154: 18.77
+	Mm
		454946 PTPRM_MOUSE (11-194): 2.59e-13: 78.2: 21.76		CADH1_MOUSE (1-485): 3.32e-54: 206: 17.93
+	Hs
		580201 PTPRG_HUMAN (1973-2270): 5.52e-25: 116: 31.19		CADH2_HUMAN (1-371): 1.8e-37: 154: 18.77
+	Hs
		580229 PTPRJ_HUMAN (5-469): 3.79e-23: 110: 14.40		CADH2_HUMAN (1-371): 1.8e-37: 154: 18.77