HitPredict

Interactor 1: PTPRQ (P0C5E4)
Phosphatidylinositol phosphatase PTPRQ (EC 3.1.3.-) (Receptor-type tyrosine-protein phosphatase Q) (PTP-RQ) (R-PTP-Q) (EC 3.1.3.48)
Gene: PTPRQ

Interactor 2: PLAK (Q02257)
Junction plakoglobin (Desmoplakin III) (Desmoplakin-3)
Gene: Jup

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	16973135
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2300 Mm			1 745
+	Mm
		472764 PTPRQ_MOUSE (1-2300): 0: 1552: 100.00		CTNB1_MOUSE (1-731): 1.33e-178: 532: 66.85
+	Mm
		472762 PTPRQ_MOUSE (1-2300): 0: 1552: 100.00		CTND1_MOUSE (207-730): 5.24e-89: 301: 15.84
+	Hs
		489895 PTPRF_HUMAN (8-1003): 1.12e-99: 360: 18.17		PLAK_HUMAN (1-745): 0: 548: 98.39
+	Mm
		56908 PTPRF_MOUSE (8-984): 1.19e-101: 367: 18.18		CTNB1_MOUSE (1-731): 1.33e-178: 532: 66.85
+	Rn
		1145481 PTPRF_RAT (8-984): 2.51e-100: 362: 17.99		CTNB1_RAT (1-731): 7.11e-179: 532: 66.85
+	Hs
		489914 PTPRF_HUMAN (8-1003): 1.12e-99: 360: 18.17		CTNB1_HUMAN (1-731): 6.24e-179: 532: 66.85
+	Hs
		717127 PTPRO_HUMAN (1975-2257): 1.54e-73: 273: 47.02		CTNB1_HUMAN (1-731): 6.24e-179: 532: 66.85
+	Hs
		576992 PTPRA_HUMAN (1998-2257): 1.51e-45: 181: 37.50		CTNB1_HUMAN (1-731): 6.24e-179: 532: 66.85
+	Dm
		333111 SDK_DROME (2-759): 8.81e-60: 231: 16.89		ARM_DROME (2-730): 3.36e-158: 481: 60.05
+	Hs
		441183 PTPRC_HUMAN (2004-2267): 3.54e-32: 140: 30.17		CTNB1_HUMAN (1-731): 6.24e-179: 532: 66.85
+	Hs
		542300 PTPRJ_HUMAN (5-469): 3.79e-23: 110: 14.40		PLAK_HUMAN (1-745): 0: 548: 98.39
+	Hs
		617080 PTPRG_HUMAN (1973-2270): 5.52e-25: 116: 31.19		CTNB1_HUMAN (1-731): 6.24e-179: 532: 66.85
+	Hs
		717036 PTPRJ_HUMAN (5-469): 3.79e-23: 110: 14.40		CTNB1_HUMAN (1-731): 6.24e-179: 532: 66.85
+	Hs
		717247 PTPRU_HUMAN (17-191): 1.5e-16: 88.9: 15.30		CTNB1_HUMAN (1-731): 6.24e-179: 532: 66.85
+	Dm
		578796 Q9W4F5_DROME (3-668): 1.1e-28: 129: 13.13		ARM_DROME (2-730): 3.36e-158: 481: 60.05
+	Dm
		90970 E1JJE4_DROME (3-668): 1.79e-28: 128: 13.13		ARM_DROME (2-730): 3.36e-158: 481: 60.05
+	Dm
		561758 PTP69_DROME (220-702): 1.85e-23: 111: 12.27		ARM_DROME (2-730): 3.36e-158: 481: 60.05
+	Hs
		239047 PTPRA_HUMAN (1998-2257): 1.51e-45: 181: 37.50		CTND1_HUMAN (203-728): 4.24e-85: 291: 15.96
+	Hs
		362959 FINC_HUMAN (445-1883): 1.66e-104: 377: 14.62		IMA1_HUMAN (430-697): 3.47e-18: 90.4: 12.29
+	Hs
		239120 PTPRJ_HUMAN (5-469): 3.79e-23: 110: 14.40		CTND1_HUMAN (203-728): 4.24e-85: 291: 15.96