HitPredict

Interactor 1: RAP1 (P08645)
Ras-related protein Rap1 (EC 3.6.5.2) (Rap1 GTPase) (Ras-like protein 3)
Gene: RAP1

Interactor 2: Q24279 (Q24279)
Cno
Gene: cno

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	1.00	0.492

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DIL~Ras, PDZ~Ras, RA~Ras
Common GO terms	GO:0007391 - dorsal closure
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Dm			1 1893
+	Dm
		473562 RAP1_DROME (1-184): 3.15e-88: 258: 100.00		Q95TT5_DROME (1-516): 5.99e-172: 577: 95.56
+	Hs
		936289 RAP1A_HUMAN (1-184): 5.32e-88: 257: 85.95		AFAD_HUMAN (484-1629): 1.64e-118: 418: 28.64
+	Dm
		473555 RAP1_DROME (1-184): 3.15e-88: 258: 100.00		Q8IPP3_DROME (484-1602): 4.77e-110: 391: 46.29
+	Hs
		976588 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		MYO5C_HUMAN (48-782): 1.52e-98: 355: 12.04
+	Zm
		14476 B4FNJ6_MAIZE (4-178): 4.34e-74: 223: 34.46		A0A1D6G388_MAIZE (86-783): 3.99e-91: 332: 13.58
+	Rn
		976726 RB11A_RAT (4-179): 8.48e-76: 228: 28.81		MYO5B_RAT (485-777): 4.66e-64: 244: 16.77
+	Hs
		976488 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		KI16B_HUMAN (128-740): 4.28e-64: 243: 13.86
+	Hs
		976550 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		KI13A_HUMAN (128-631): 9.93e-62: 236: 15.06
+	Hs
		976691 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		MYO5A_HUMAN (57-783): 1.73e-58: 226: 12.50
+	Hs
		976658 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		MYO5B_HUMAN (60-801): 4.87e-55: 215: 11.63
+	Hs
		976587 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		KI13B_HUMAN (249-722): 1.88e-54: 213: 13.83
+	Hs
		1155402 RB11B_HUMAN (4-176): 2.43e-74: 224: 29.89		MYO5B_HUMAN (60-801): 4.87e-55: 215: 11.63
+	Hs
		976579 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		GOPC_HUMAN (579-1000): 4.92e-58: 210: 15.62
+	Hs
		956502 RAB2A_HUMAN (4-170): 1.01e-73: 222: 38.10		GOPC_HUMAN (579-1000): 4.92e-58: 210: 15.62
+	Mm
		981402 RAB1A_MOUSE (4-170): 8.44e-77: 229: 34.52		NEB2_MOUSE (826-961): 1.52e-38: 158: 34.53
+	Mm
		956835 RAB8B_MOUSE (4-180): 8.94e-74: 222: 33.15		NEB2_MOUSE (826-961): 1.52e-38: 158: 34.53
+	Hs
		982122 RAP1A_HUMAN (1-184): 5.32e-88: 257: 85.95		RADIL_HUMAN (713-941): 1.19e-21: 104: 20.35
+	Hs
		976264 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		SCRIB_HUMAN (741-1068): 8.89e-24: 112: 15.32
+	Hs
		976235 RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81		DLG1_HUMAN (810-939): 4.15e-12: 73.7: 24.43
+	Hs
		956270 RAB2A_HUMAN (4-170): 1.01e-73: 222: 38.10		DLG1_HUMAN (810-939): 4.15e-12: 73.7: 24.43