HitPredict

Interactor 1: RASK (P32883)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: Kras

Interactor 2: Q9JJU6 (Q9JJU6)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: Braf

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, RBD~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Mm			1 373
+	Hs
		374377 RASH_HUMAN (1-188): 8.01e-87: 254: 86.77		BRAF_HUMAN (1-373): 0: 567: 94.39
+	Hs
		373754 RASN_HUMAN (1-189): 7.32e-86: 252: 86.24		BRAF_HUMAN (1-373): 0: 567: 94.39
+	Hs
		375142 RASK_HUMAN (16-189): 8.56e-79: 234: 98.85		BRAF_HUMAN (1-373): 0: 567: 94.39
+	Mm
		700351 RASH_MOUSE (1-188): 8.01e-87: 254: 86.77		BRAF_MOUSE (1-356): 0: 533: 90.73
+	Rn
		541167 RASH_RAT (1-188): 8.01e-87: 254: 86.77		RAF1_RAT (40-372): 4.85e-136: 404: 37.36
+	Hs
		374327 RASH_HUMAN (1-188): 8.01e-87: 254: 86.77		RAF1_HUMAN (40-372): 1.18e-135: 403: 37.07
+	Mm
		1222734 RASH_MOUSE (1-188): 8.01e-87: 254: 86.77		RAF1_MOUSE (40-372): 2.38e-135: 402: 37.07
+	Hs
		373722 RASN_HUMAN (1-189): 7.32e-86: 252: 86.24		RAF1_HUMAN (40-372): 1.18e-135: 403: 37.07
+	Rn
		473535 RASK_RAT (16-189): 3.42e-79: 235: 100.00		RAF1_RAT (40-372): 4.85e-136: 404: 37.36
+	Hs
		375069 RASK_HUMAN (16-189): 8.56e-79: 234: 98.85		RAF1_HUMAN (40-372): 1.18e-135: 403: 37.07
+	Mm
		746565 RASK_MOUSE (16-189): 3.42e-79: 235: 100.00		RAF1_MOUSE (40-372): 2.38e-135: 402: 37.07
+	Rn
		569433 RASH_RAT (1-188): 8.01e-87: 254: 86.77		ARAF_RAT (75-371): 6.77e-125: 374: 41.25
+	Hs
		374357 RASH_HUMAN (1-188): 8.01e-87: 254: 86.77		ARAF_HUMAN (75-371): 9.93e-125: 373: 42.95
+	Hs
		373741 RASN_HUMAN (1-189): 7.32e-86: 252: 86.24		ARAF_HUMAN (75-371): 9.93e-125: 373: 42.95
+	Mm
		411153 RASH_MOUSE (1-188): 8.01e-87: 254: 86.77		ARAF_MOUSE (75-371): 1.28e-123: 370: 41.25
+	Hs
		374136 RASN_HUMAN (1-189): 7.32e-86: 252: 86.24		Q96II5_HUMAN (75-371): 3.3e-123: 369: 42.62
+	Hs
		375113 RASK_HUMAN (16-189): 8.56e-79: 234: 98.85		ARAF_HUMAN (75-371): 9.93e-125: 373: 42.95
+	Mm
		411149 RASK_MOUSE (16-189): 3.42e-79: 235: 100.00		ARAF_MOUSE (75-371): 1.28e-123: 370: 41.25
+	Dm
		473590 RAS1_DROME (1-165): 3e-88: 258: 86.06		KRAF1_DROME (1-371): 1.87e-109: 338: 30.18
+	Ce
		653993 LET60_CAEEL (1-189): 5.13e-86: 252: 75.13		KRAF1_CAEEL (79-330): 1.28e-81: 267: 31.27