HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBP42 (Q9H9J4)
Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.4.19.12) (Deubiquitinating enzyme 42) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42)
Gene: USP42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	29576527
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 1324
+	Hs
		475932 UBC_HUMAN (1-685): 0: 846: 100.00		U17L2_HUMAN (46-541): 9.83e-122: 390: 44.67
+	Hs
		64200 UBC_HUMAN (1-685): 0: 846: 100.00		UBP27_HUMAN (41-429): 4.98e-112: 361: 23.15
+	Hs
		476579 UBC_HUMAN (1-685): 0: 846: 100.00		UBP22_HUMAN (81-413): 1.9e-109: 357: 26.58
+	Hs
		259261 UBC_HUMAN (1-685): 0: 846: 100.00		UBP12_HUMAN (90-403): 1.11e-104: 338: 23.58
+	Hs
		475566 UBC_HUMAN (1-685): 0: 846: 100.00		UBP46_HUMAN (90-403): 8.36e-105: 338: 24.48
+	Hs
		271022 UBC_HUMAN (1-685): 0: 846: 100.00		UBP2_HUMAN (33-417): 1.27e-100: 335: 25.65
+	Hs
		475995 UBC_HUMAN (1-685): 0: 846: 100.00		UBP48_HUMAN (66-505): 2.07e-91: 321: 18.07
+	Hs
		476658 UBC_HUMAN (1-685): 0: 846: 100.00		UBP3_HUMAN (39-413): 1.26e-96: 321: 25.76
+	Dm
		477538 UBIQP_DROME (1-610): 0: 752: 99.84		NOT_DROME (87-412): 1.72e-100: 331: 25.91
+	Hs
		475954 UBC_HUMAN (1-685): 0: 846: 100.00		UBP31_HUMAN (109-269): 1.57e-31: 136: 22.40
+	Hs
		476493 UBC_HUMAN (1-685): 0: 846: 100.00		UBP36_HUMAN (558-1131): 6.82e-10: 66.1: 8.87
+	At
		1210479 UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80		UBP15_ARATH (10-559): 1.02e-106: 361: 29.77
+	Sc
		477294 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP5_YEAST (8-411): 5.77e-102: 345: 23.92
+	Sc
		477366 UBI4P_YEAST (381-685): 5e-122: 370: 95.74		UBP8_YEAST (109-413): 1.93e-95: 316: 28.19
+	At
		1092065 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP15_ARATH (10-559): 1.02e-106: 361: 29.77
+	At
		1092066 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP12_ARATH (23-451): 8.76e-90: 318: 18.61
+	At
		1091741 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		UBP13_ARATH (23-404): 1.35e-88: 314: 19.30
+	Mm
		476741 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP46_MOUSE (90-403): 8.36e-105: 338: 24.48
+	Mm
		476939 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		UBP3_MOUSE (39-416): 3.98e-95: 318: 25.12
+	Hs
		924201 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		UBP36_HUMAN (558-1131): 6.82e-10: 66.1: 8.87