HitPredict

Interactor 1: UBI4P (P0CG63)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBI4

Interactor 2: EDE1 (P34216)
EH domain-containing and endocytosis protein 1 (Bud site selection protein 15)
Gene: EDE1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.962

Property	Details
Experiments	11988742, 38803224, 16563434, 16007098, 28525741, 19903324, 19620964
Identification Methods	pull down, x-ray crystallography, affinity chromatography technology
Interaction Type	direct interaction, association, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 381 Sc			1 1381
+	Mm
		476828 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		MYH10_MOUSE (319-973): 1.3e-24: 114: 8.22
+	Mm
		476930 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		MYH9_MOUSE (348-894): 3.1e-21: 103: 8.55
+	Mm
		222609 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		REPS1_MOUSE (2-488): 3.96e-21: 102: 13.22
+	Mm
		477062 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		ITSN1_MOUSE (730-1084): 3.21e-14: 80.4: 12.29
+	Mm
		70590 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		B2RR82_MOUSE (897-1291): 1.5e-12: 75: 9.11
+	Mm
		476822 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		EP15R_MOUSE (835-1022): 4.78e-12: 73: 10.11
+	Rn
		88639 UBC_RAT (1-333): 8.71e-131: 395: 93.99		D3ZJR1_RAT (835-1022): 1.2e-11: 71.5: 10.64
+	Mm
		476700 UBC_MOUSE (1-333): 9.24e-132: 396: 93.99		EPS15_MOUSE (786-953): 2.57e-09: 64.2: 10.59
+	Rn
		1126748 UBC_RAT (1-333): 8.71e-131: 395: 93.99		Q5JC29_RAT (692-854): 2.58e-09: 63.8: 12.58
+	Hs
		475417 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		MYH9_HUMAN (562-1329): 1.43e-32: 140: 9.13
+	Hs
		475816 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		ITSN1_HUMAN (753-1128): 2.65e-16: 87.3: 12.27
+	Hs
		476483 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		ITSN2_HUMAN (825-1202): 1.33e-15: 85: 9.44
+	Hs
		475291 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		MYH1_HUMAN (836-1327): 1.02e-14: 81.9: 10.51
+	Hs
		476502 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		EP15R_HUMAN (849-1039): 2.63e-13: 76.9: 8.38
+	Hs
		397813 ISG15_HUMAN (3-152): 9.45e-31: 117: 32.68		MYH9_HUMAN (562-1329): 1.43e-32: 140: 9.13
+	Hs
		475452 UBC_HUMAN (1-153): 1.84e-50: 181: 95.43		EPS15_HUMAN (583-757): 7.71e-11: 68.8: 14.86
+	Hs
		397814 ISG15_HUMAN (3-152): 9.45e-31: 117: 32.68		MYH10_HUMAN (319-973): 9.5e-25: 115: 7.92