HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: TIAR (Q01085)
Nucleolysin TIAR (TIA-1-related protein)
Gene: TIAL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	32296183, 35271311, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 375
+	Hs
		47973 RBM47_HUMAN (12-281): 2.31e-39: 146: 18.68		TIAR_HUMAN (1-375): 6.14e-100: 302: 100.00
+	Hs
		550237 PABP1_HUMAN (10-223): 3.85e-20: 91.9: 14.82		TIAR_HUMAN (1-375): 6.14e-100: 302: 100.00
+	Hs
		47977 RBM47_HUMAN (12-281): 2.31e-39: 146: 18.68		PABP4_HUMAN (2-302): 1.5e-65: 221: 23.70
+	Hs
		477926 SNRPA_HUMAN (1-282): 1.06e-59: 193: 100.00		TIA1_HUMAN (3-213): 4.58e-33: 129: 22.08
+	Sc
		403419 RU1A_YEAST (1-281): 3.83e-48: 163: 20.42		PABP_YEAST (1-197): 1.01e-39: 150: 23.59
+	Hs
		550262 PABP1_HUMAN (10-223): 3.85e-20: 91.9: 14.82		PABP4_HUMAN (2-302): 1.5e-65: 221: 23.70
+	Hs
		344105 PTBP3_HUMAN (2-281): 3.3e-49: 172: 19.44		TIA1_HUMAN (3-213): 4.58e-33: 129: 22.08
+	Sc
		403417 PUB1_YEAST (11-282): 2.92e-39: 144: 18.25		PABP_YEAST (1-197): 1.01e-39: 150: 23.59
+	Sc
		740827 PUB1_YEAST (11-282): 2.92e-39: 144: 18.25		PUB1_YEAST (9-176): 2.98e-33: 130: 42.60
+	Sc
		403283 PABP_YEAST (10-199): 1.97e-17: 83.8: 10.42		PABP_YEAST (1-197): 1.01e-39: 150: 23.59
+	Hs
		550137 PABP1_HUMAN (10-223): 3.85e-20: 91.9: 14.82		TIA1_HUMAN (3-213): 4.58e-33: 129: 22.08
+	Hs
		550464 PABP1_HUMAN (10-223): 3.85e-20: 91.9: 14.82		PABP3_HUMAN (87-294): 2.48e-32: 129: 23.59
+	Hs
		47949 RBM47_HUMAN (12-281): 2.31e-39: 146: 18.68		PABP1_HUMAN (195-285): 9e-13: 71.7: 25.77
+	Hs
		1102095 PABP4_HUMAN (11-199): 2.34e-18: 86.5: 18.42		PABP3_HUMAN (87-294): 2.48e-32: 129: 23.59
+	Hs
		550097 PABP1_HUMAN (10-223): 3.85e-20: 91.9: 14.82		PABP1_HUMAN (195-285): 9e-13: 71.7: 25.77
+	Mm
		710979 PABP1_MOUSE (10-223): 3.78e-20: 91.9: 14.82		TIA1_MOUSE (1-99): 5.43e-13: 71.7: 25.25
+	Hs
		550311 PABP1_HUMAN (10-223): 3.85e-20: 91.9: 14.82		PAP1L_HUMAN (202-285): 2.62e-12: 70.1: 23.33
+	Hs
		506129 PABP4_HUMAN (11-199): 2.34e-18: 86.5: 18.42		PAB4L_HUMAN (196-285): 3.17e-11: 65.9: 19.79
+	Zm
		8282 A0A1D6ELH4_MAIZE (8-218): 1.21e-18: 87.6: 20.37		A0A1D6ELH4_MAIZE (202-287): 2.46e-10: 64: 21.74