HitPredict

Interactor 1: CD48 (P09326)
CD48 antigen (B-lymphocyte activation marker BLAST-1) (BCM1 surface antigen) (Leukocyte antigen MEM-102) (SLAM family member 2) (SLAMF2) (Signaling lymphocytic activation molecule 2) (TCT.1) (CD antigen CD48)
Gene: CD48

Interactor 2: CD244 (Q9BZW8)
Natural killer cell receptor 2B4 (NK cell activation-inducing ligand) (NAIL) (NK cell type I receptor protein 2B4) (NKR2B4) (h2B4) (SLAM family member 4) (SLAMF4) (Signaling lymphocytic activation molecule 4) (CD antigen CD244)
Gene: CD244

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	18296487, 16002700, 15153464
Identification Methods	solid phase assay, fluorescence-activated cell sorting
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Receptor_2B4~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0006955 - immune response GO:0030101 - natural killer cell activation GO:0045121 - membrane raft
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 243 Hs			1 370
+	Hs
		1460352 SLAF5_HUMAN (10-242): 2.49e-59: 192: 18.33		SLAF5_HUMAN (2-345): 8.36e-62: 203: 21.57
+	Hs
		480434 CD48_HUMAN (1-243): 2.14e-75: 230: 100.00		CD48_HUMAN (20-247): 3.75e-47: 162: 21.55
+	Hs
		445472 CD48_HUMAN (1-243): 2.14e-75: 230: 100.00		CD2_HUMAN (9-362): 8.42e-43: 153: 13.19
+	Hs
		1387867 SLAF6_HUMAN (14-242): 7.95e-52: 172: 17.55		SLAF6_HUMAN (2-332): 1.08e-57: 192: 18.71
+	Hs
		1446664 SLAF7_HUMAN (12-221): 1.91e-58: 189: 18.14		SLAF7_HUMAN (1-345): 2.07e-50: 173: 18.29
+	Hs
		1101252 SLAF1_HUMAN (11-242): 1.58e-54: 179: 21.83		SLAF1_HUMAN (1-325): 6.16e-49: 169: 19.53
+	Hs
		567234 CEAM8_HUMAN (6-211): 5.82e-59: 191: 16.97		CEAM1_HUMAN (7-321): 3.75e-41: 153: 17.83
+	Hs
		567239 CEAM7_HUMAN (6-211): 8.79e-57: 183: 18.27		CEAM1_HUMAN (7-321): 3.75e-41: 153: 17.83
+	Hs
		731822 CEAM8_HUMAN (6-211): 5.82e-59: 191: 16.97		CEAM6_HUMAN (55-247): 6.97e-23: 100: 13.99
+	Hs
		731819 CEAM8_HUMAN (6-211): 5.82e-59: 191: 16.97		CEAM8_HUMAN (55-247): 3.46e-20: 92.3: 12.31
+	Hs
		820637 CEAM7_HUMAN (6-211): 8.79e-57: 183: 18.27		CEAM6_HUMAN (55-247): 6.97e-23: 100: 13.99
+	Hs
		1027931 PSG11_HUMAN (6-211): 3.7e-57: 186: 19.09		PSG4_HUMAN (45-220): 1.1e-20: 94.6: 14.21
+	Hs
		445628 CEAM5_HUMAN (94-211): 1.98e-23: 100: 18.25		CEAM1_HUMAN (7-321): 3.75e-41: 153: 17.83
+	Hs
		820595 CEAM3_HUMAN (6-130): 1.41e-28: 110: 16.15		CEAM3_HUMAN (4-131): 2.02e-27: 110: 21.21
+	Hs
		445630 CEAM5_HUMAN (94-211): 1.98e-23: 100: 18.25		CEAM6_HUMAN (55-247): 6.97e-23: 100: 13.99
+	Hs
		445627 CEAM5_HUMAN (94-211): 1.98e-23: 100: 18.25		CEAM5_HUMAN (55-246): 1.45e-21: 98.1: 13.54
+	Hs
		543416 PSG1_HUMAN (85-211): 1.28e-22: 97.1: 18.66		PSG4_HUMAN (45-220): 1.1e-20: 94.6: 14.21
+	Hs
		543417 PSG1_HUMAN (85-211): 1.28e-22: 97.1: 18.66		PSG6_HUMAN (55-230): 7.33e-19: 89.2: 13.07
+	Hs
		543415 PSG1_HUMAN (85-211): 1.28e-22: 97.1: 18.66		PSG9_HUMAN (45-221): 1.19e-17: 85.8: 14.69