Protein: CD2
T-cell surface antigen CD2 (Erythrocyte receptor) (LFA-2) (LFA-3 receptor) (Rosette receptor) (T-cell surface antigen T11/Leu-5) (CD antigen CD2)

Gene: CD2
Organism: Homo sapiens
Interactions: 19
UniProt ID: P06729

Gene Ontology (top 5):
GO:0001766 - membrane raft polarization
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

445483

CD2AP
CD2-associated protein

5

10

Small-scale

0.725

High

335764

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

6

0

Small-scale

0.713

High

445480

SH3K1
SH3 domain-containing kinase-binding protein 1

3

9

Small-scale

0.688

High

445473

LEG1
Galectin-1

1

14

Small-scale

0.665

High

445471

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

18

Small-scale

0.647

High

445472

CD48
CD48 antigen

1

19

Small-scale

0.647

High

445474

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.647

High

445476

CD53
Leukocyte surface antigen CD53

1

10

Small-scale

0.618

High

220731

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

2

0

Small-scale

0.610

High

439900

LCK
Tyrosine-protein kinase Lck

2

16

Small-scale

0.602

High

445475

LFA3
Lymphocyte function-associated antigen 3

2

0

Small-scale

0.592

High

445479

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.586

High

440293

FYN
Tyrosine-protein kinase Fyn

1

16

Small-scale

0.569

High

445482

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.518

High

445481

DNJC5
DnaJ homolog subfamily C member 5

1

5

High-throughput

0.501

High

370934

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

438924

CD5
T-cell surface glycoprotein CD5

1

4

Small-scale

0.479

High

445477

ITK
Tyrosine-protein kinase ITK/TSK

1

17

Small-scale

0.479

High

445478

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.457

High


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Last updated: 11Aug2025