Protein: SLAF1
Signaling lymphocytic activation molecule (CDw150) (IPO-3) (SLAM family member 1) (CD antigen CD150)

Gene: SLAF1, SLAMF1
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q13291

Gene Ontology (top 5):
GO:0001618 - virus receptor activity
GO:0001779 - natural killer cell differentiation
GO:0001787 - natural killer cell proliferation
GO:0002232 - leukocyte chemotaxis involved in inflammatory response
GO:0002250 - adaptive immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

258595

SH21A
SH2 domain-containing protein 1A

15

20

Small-scale

0.762

High

931231

AT12A
Potassium-transporting ATPase alpha chain 2

3

6

High-throughput

0.667

High

1053656

PTN11
Tyrosine-protein phosphatase non-receptor type 11

3

20

Small-scale

0.643

High

1101292

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

2

15

Small-scale

0.639

High

1101252

SLAF1
Signaling lymphocytic activation molecule

2

18

Small-scale

0.629

High

164857

SH21B
SH2 domain-containing protein 1B

3

20

Small-scale

0.623

High

480780

LEG1
Galectin-1

2

11

High-throughput

0.611

High

565612

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

2

6

High-throughput

0.611

High

630509

RAB3B
Ras-related protein Rab-3B

2

6

High-throughput

0.611

High

732812

GLPK
Glycerol kinase

2

2

High-throughput

0.611

High

845021

EAA3
Excitatory amino acid transporter 3

2

3

High-throughput

0.611

High

996930

TBA4A
Tubulin alpha-4A chain

2

10

High-throughput

0.611

High

1032578

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

7

High-throughput

0.611

High

1101258

GLPK2
Glycerol kinase 2

2

2

High-throughput

0.611

High

1101262

OCLN
Occludin

2

3

High-throughput

0.611

High

1101263

AT2B3
Plasma membrane calcium-transporting ATPase 3

2

10

High-throughput

0.611

High

1101282

S39AB
Zinc transporter ZIP11

2

3

High-throughput

0.611

High

1101290

ELYS
Protein ELYS

2

4

High-throughput

0.611

High

1101301

MYADM
Myeloid-associated differentiation marker

2

2

High-throughput

0.611

High

1101309

ANTR1
Anthrax toxin receptor 1

2

6

High-throughput

0.611

High

1101310

RAB18
Ras-related protein Rab-18

2

11

High-throughput

0.611

High

1101320

STML1
Stomatin-like protein 1

2

3

High-throughput

0.611

High

942488

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

3

3

High-throughput

0.609

High

168015

RGS13
Regulator of G-protein signaling 13

2

0

High-throughput

0.602

High

1101303

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

2

2

High-throughput

0.574

High

244087

ZN292
Zinc finger protein 292

2

1

High-throughput

0.558

High

665090

COT2
COUP transcription factor 2

2

4

High-throughput

0.558

High

1101257

URB2
Unhealthy ribosome biogenesis protein 2 homolog

2

1

High-throughput

0.558

High

1101271

HEAT6
HEAT repeat-containing protein 6

2

2

High-throughput

0.558

High

1101299

INT4
Integrator complex subunit 4

2

1

High-throughput

0.558

High

1101308

HEAT1
HEAT repeat-containing protein 1

2

2

High-throughput

0.558

High

1101312

UFSP2
Ufm1-specific protease 2

2

4

High-throughput

0.558

High

1101313

INT7
Integrator complex subunit 7

2

1

High-throughput

0.558

High

1101322

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

2

1

High-throughput

0.558

High

1101325

ORNT1
Mitochondrial ornithine transporter 1

2

3

High-throughput

0.558

High

1101326

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

2

10

High-throughput

0.558

High

1101327

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

2

10

High-throughput

0.558

High

163295

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

10

High-throughput

0.536

High

269664

PLXA2
Plexin-A2

1

8

High-throughput

0.536

High

323988

CSTN1
Calsyntenin-1

1

20

High-throughput

0.536

High

337530

LARG1
Xylosyl- and glucuronyltransferase LARGE1

1

3

High-throughput

0.536

High

441424

CHLE
Cholinesterase

1

6

High-throughput

0.536

High

465507

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.536

High

599110

CBPE
Carboxypeptidase E

1

7

High-throughput

0.536

High

710623

EPHA3
Ephrin type-A receptor 3

1

20

High-throughput

0.536

High

756546

GALNS
N-acetylgalactosamine-6-sulfatase

1

5

High-throughput

0.536

High

841608

LIFR
Leukemia inhibitory factor receptor

1

11

High-throughput

0.536

High

932362

ANAG
Alpha-N-acetylglucosaminidase

1

1

High-throughput

0.536

High

937390

LAMB2
Laminin subunit beta-2

1

11

High-throughput

0.536

High

1101254

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

4

High-throughput

0.536

High

1101255

TBB3
Tubulin beta-3 chain

1

9

High-throughput

0.536

High

1101256

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

9

High-throughput

0.536

High

1101259

BECN1
Beclin-1

1

1

Small-scale

0.536

High

1101260

FAT1
Protocadherin Fat 1

1

16

High-throughput

0.536

High

1101264

LAMA3
Laminin subunit alpha-3

1

15

High-throughput

0.536

High

1101265

T132A
Transmembrane protein 132A

1

1

High-throughput

0.536

High

1101269

GT253
Inactive glycosyltransferase 25 family member 3

1

2

High-throughput

0.536

High

1101275

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

13

High-throughput

0.536

High

1101276

AN13D
Ankyrin repeat domain-containing protein 13D

1

6

High-throughput

0.536

High

1101277

MON2
Protein MON2 homolog

1

9

High-throughput

0.536

High

1101279

FRAS1
Extracellular matrix organizing protein FRAS1

1

20

High-throughput

0.536

High

1101289

AGRV1
Adhesion G-protein coupled receptor V1

1

19

High-throughput

0.536

High

1101298

I17RA
Interleukin-17 receptor A

1

1

High-throughput

0.536

High

1101306

CNTP3
Contactin-associated protein-like 3

1

16

High-throughput

0.536

High

1101315

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

17

High-throughput

0.536

High

1101319

UVRAG
UV radiation resistance-associated gene protein

1

1

Small-scale

0.536

High

1101323

SIA10
Type 2 lactosamine alpha-2,3-sialyltransferase

1

1

High-throughput

0.536

High

600608

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.513

High

720413

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

0

High-throughput

0.513

High

440537

FYN
Tyrosine-protein kinase Fyn

1

20

Small-scale

0.501

High

135804

RTCA
RNA 3'-terminal phosphate cyclase

1

1

High-throughput

0.489

High

318133

IPO13
Importin-13

1

10

High-throughput

0.489

High

337257

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

6

High-throughput

0.489

High

547140

PYC
Pyruvate carboxylase, mitochondrial

1

6

High-throughput

0.489

High

552224

ADT3
ADP/ATP translocase 3

1

2

High-throughput

0.489

High

611726

BMP7
Bone morphogenetic protein 7

1

5

High-throughput

0.489

High

1041655

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

4

High-throughput

0.489

High

1101253

OS9
Protein OS-9

1

2

High-throughput

0.489

High

1101261

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

1

High-throughput

0.489

High

1101266

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

1

High-throughput

0.489

High

1101268

ODR4
Protein odr-4 homolog

1

4

High-throughput

0.489

High

1101270

CAHD1
VWFA and cache domain-containing protein 1

1

4

High-throughput

0.489

High

1101272

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

8

High-throughput

0.489

High

1101273

MOXD1
DBH-like monooxygenase protein 1

1

2

High-throughput

0.489

High

1101274

ARSK
Arylsulfatase K

1

5

High-throughput

0.489

High

1101278

ANR46
Ankyrin repeat domain-containing protein 46

1

17

High-throughput

0.489

High

1101285

MROH1
Maestro heat-like repeat-containing protein family member 1

1

1

High-throughput

0.489

High

1101286

PK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

5

Small-scale

0.489

High

1101291

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

9

High-throughput

0.489

High

1101293

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

9

Small-scale

0.489

High

1101294

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

7

High-throughput

0.489

High

1101296

ATG2B
Autophagy-related protein 2 homolog B

1

1

High-throughput

0.489

High

1101300

TXD15
Thioredoxin domain-containing protein 15

1

7

High-throughput

0.489

High

1101302

DHRS9
Dehydrogenase/reductase SDR family member 9

1

3

High-throughput

0.489

High

1101314

FANCI
Fanconi anemia group I protein

1

3

High-throughput

0.489

High

1101316

KBRS1
NF-kappa-B inhibitor-interacting Ras-like protein 1

1

20

High-throughput

0.489

High

1101321

SE1L1
Protein sel-1 homolog 1

1

5

High-throughput

0.489

High

471742

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

16

Small-scale

0.479

High

486690

FGR
Tyrosine-protein kinase Fgr

1

20

Small-scale

0.479

High

631200

RAB5A
Ras-related protein Rab-5A

1

8

High-throughput

0.479

High

637892

NF1
Neurofibromin

1

7

High-throughput

0.479

High

1015013

ARF5
ADP-ribosylation factor 5

1

11

High-throughput

0.479

High

1101280

AN13A
Ankyrin repeat domain-containing protein 13A

1

3

High-throughput

0.479

High

1101317

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

1

High-throughput

0.479

High

1101305

SGPP1
Sphingosine-1-phosphate phosphatase 1

1

0

High-throughput

0.458

High

1101324

S27A6
Long-chain fatty acid transport protein 6

1

0

High-throughput

0.458

High

219950

XRCC3
DNA repair protein XRCC3

1

1

High-throughput

0.437

High

261718

HUS1
Checkpoint protein HUS1

1

2

High-throughput

0.437

High

317838

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.437

High

354330

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

2

High-throughput

0.437

High

1101267

NU188
Nucleoporin NUP188

1

1

High-throughput

0.437

High

1101288

PTCD2
Pentatricopeptide repeat-containing protein 2, mitochondrial

1

1

High-throughput

0.437

High

1101307

INT2
Integrator complex subunit 2

1

2

High-throughput

0.437

High

1101311

PYRG2
CTP synthase 2

1

2

High-throughput

0.437

High

1101318

MTCH1
Mitochondrial carrier homolog 1

1

5

High-throughput

0.437

High

296118

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

2

0

High-throughput

0.318

High

651794

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

2

0

High-throughput

0.318

High

1101281

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

0

High-throughput

0.318

High

1101295

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

2

0

High-throughput

0.318

High

317451

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

1

0

High-throughput

0.279

Low

1101284

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1101304

THUM3
tRNA

1

0

High-throughput

0.279

Low

1101283

INT1
Integrator complex subunit 1

1

0

High-throughput

0.249

Low

1101287

CHPT1
Cholinephosphotransferase 1

1

0

High-throughput

0.249

Low

1101297

INT12
Integrator complex subunit 12

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025