HitPredict

Interactor 1: CEAM5 (P06731)
Cell adhesion molecule CEACAM5 (Carcinoembryonic antigen) (CEA) (Carcinoembryonic antigen-related cell adhesion molecule 5) (CEA cell adhesion molecule 5) (Meconium antigen 100) (CD antigen CD66e)
Gene: CEACAM5

Interactor 2: CEAM5 (P06731)
Cell adhesion molecule CEACAM5 (Carcinoembryonic antigen) (CEA) (Carcinoembryonic antigen-related cell adhesion molecule 5) (CEA cell adhesion molecule 5) (Meconium antigen 100) (CD antigen CD66e)
Gene: CEACAM5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 26483485, 18086185
Identification Methods cosedimentation in solution, x-ray crystallography, molecular sieving, surface plasmon resonance, cosedimentation through density gradient, comigration in sds page
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ig_2~Ig_2, Ig_2~Ig_3, Ig_2~V-set, Ig_3~Ig_3, Ig_3~V-set, V-set~V-set
Common GO terms GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
and 12 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Last updated: 11Aug2025