HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38334954
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005615 - extracellular space GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 248
+	Hs
		186636 HMGB3_HUMAN (13-181): 1.46e-41: 141: 71.60		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		481219 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		730446 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		1433S_HUMAN (1-248): 3.5e-158: 440: 100.00
+	Hs
		872154 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		872178 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		971907 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		1433E_HUMAN (2-246): 4.43e-146: 410: 60.41
+	Hs
		990631 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		1433Z_HUMAN (1-242): 8.34e-142: 398: 70.66
+	Hs
		481103 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		481119 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62
+	Hs
		481190 HMGB1_HUMAN (1-174): 9.5e-45: 150: 100.00		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		966241 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		1049231 SSRP1_HUMAN (53-164): 1.6e-28: 114: 37.50		1433F_HUMAN (2-242): 2.79e-96: 283: 64.20
+	Hs
		872150 SOX2_HUMAN (3-94): 7.23e-25: 100: 23.91		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		942085 SOX10_HUMAN (4-98): 2.08e-21: 93.2: 14.74		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		691354 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		1433T_HUMAN (1-238): 1e-107: 312: 71.85
+	Hs
		730170 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		1433B_HUMAN (1-239): 3.42e-100: 293: 68.62
+	Hs
		966775 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		1433G_HUMAN (1-242): 1.87e-98: 289: 65.16
+	Hs
		1049692 CIC_HUMAN (3-96): 6.88e-12: 65.9: 22.34		1433F_HUMAN (2-242): 2.79e-96: 283: 64.20