HitPredict

Interactor 1: E2F8 (A0AVK6)
Transcription factor E2F8 (E2F-8)
Gene: E2F8

Interactor 2: E2F7 (Q96AV8)
Transcription factor E2F7 (E2F-7)
Gene: E2F7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 18202719
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E2F_TDP~E2F_TDP
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
and 15 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 867
Hs

1 911
+ Mm
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+ At
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 11Aug2025