HitPredict

Interactor 1: E2F8 (Q58FA4)
Transcription factor E2F8 (E2F-8)
Gene: E2F8

Interactor 2: E2F8 (Q58FA4)
Transcription factor E2F8 (E2F-8)
Gene: E2F8

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 15722552
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E2F_TDP~E2F_TDP
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001217 - DNA-binding transcription repressor activity
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001890 - placenta development
and 16 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 860
Mm

1 860
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Last updated: 11Aug2025