HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0009898 - cytoplasmic side of plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 921 Hs			1 193
+	Hs
		48326 ESYT2_HUMAN (1-921): 0: 839: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		48236 ESYT2_HUMAN (1-921): 0: 839: 100.00		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		48332 ESYT2_HUMAN (1-921): 0: 839: 100.00		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		48312 ESYT2_HUMAN (1-921): 0: 839: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		48253 ESYT2_HUMAN (1-921): 0: 839: 100.00		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		48311 ESYT2_HUMAN (1-921): 0: 839: 100.00		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		48321 ESYT2_HUMAN (1-921): 0: 839: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		48172 ESYT2_HUMAN (1-921): 0: 839: 100.00		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		900846 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		925568 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436481 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		951279 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		894369 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545587 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		892564 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		915927 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120611 ESYT1_HUMAN (528-920): 4.27e-24: 111: 15.23		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		436543 MYOF_HUMAN (387-664): 4.34e-14: 79.1: 14.04		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		545663 MYOF_HUMAN (387-664): 4.34e-14: 79.1: 14.04		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		120679 MYOF_HUMAN (387-664): 4.34e-14: 79.1: 14.04		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98