HitPredict

Interactor 1: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Interactor 2: CTTB2 (Q8WZ74)
Cortactin-binding protein 2 (CortBP2)
Gene: CTTNBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4684 Hs			1 1663
+	Hs
		1091401 PLEC_HUMAN (1-4684): 0: 1793: 100.00		ANK3_HUMAN (1158-1279): 2.77e-17: 90.9: 8.66
+	Rn
		267189 PLEC_RAT (1-4684): 0: 1767: 93.35		ANK3_RAT (1158-1279): 2.39e-18: 94.3: 7.87
+	Hs
		1143141 PLEC_HUMAN (1-4684): 0: 1793: 100.00		FIL1L_HUMAN (17-283): 2.96e-10: 67.5: 18.82
+	Dm
		612406 ACTN_DROME (156-894): 5.82e-121: 410: 23.24		SICK_DROME (978-1392): 3.07e-90: 328: 24.16
+	Hs
		555645 ACTN1_HUMAN (153-894): 1.99e-116: 396: 23.90		DAPK1_HUMAN (970-1275): 2.89e-23: 110: 8.81
+	Hs
		1061544 ACTN3_HUMAN (166-891): 1.55e-120: 408: 25.86		ASB9_HUMAN (714-863): 8.16e-18: 87.8: 37.75
+	Hs
		1028813 SPTB2_HUMAN (1005-2737): 3.24e-30: 135: 9.83		NAV2_HUMAN (973-1393): 3.85e-98: 354: 24.53
+	Hs
		592928 SPTB2_HUMAN (1005-2737): 3.24e-30: 135: 9.83		ANK1_HUMAN (733-1276): 5.43e-95: 343: 10.24
+	Hs
		540235 SPTB1_HUMAN (1903-3210): 1e-21: 107: 10.84		ANK1_HUMAN (733-1276): 5.43e-95: 343: 10.24
+	Dm
		1028087 SPTCB_DROME (390-1997): 7.12e-18: 94.7: 9.69		SICK_DROME (978-1392): 3.07e-90: 328: 24.16
+	Ce
		109664 G5EBH3_CAEEL (402-1259): 1.99e-17: 93.1: 11.30		Q95QQ9_CAEEL (29-472): 3.15e-74: 260: 21.91
+	Mm
		109265 SPTB2_MOUSE (1005-2737): 1.53e-30: 136: 10.11		ANK3_MOUSE (1013-1283): 4.85e-25: 116: 6.33
+	Hs
		920429 SPTB2_HUMAN (1005-2737): 3.24e-30: 135: 9.83		DAPK1_HUMAN (970-1275): 2.89e-23: 110: 8.81
+	Hs
		1028731 SPTB2_HUMAN (1005-2737): 3.24e-30: 135: 9.83		ANK2_HUMAN (951-1283): 1.07e-22: 108: 5.52
+	Hs
		1028748 SPTB2_HUMAN (1005-2737): 3.24e-30: 135: 9.83		ANK3_HUMAN (1158-1279): 2.77e-17: 90.9: 8.66
+	Hs
		174726 SPTN2_HUMAN (1390-3107): 3.29e-22: 108: 12.11		DAPK1_HUMAN (970-1275): 2.89e-23: 110: 8.81
+	Mm
		109260 Q3UGX2_MOUSE (1516-3234): 1.53e-19: 100: 10.21		ANK3_MOUSE (1013-1283): 4.85e-25: 116: 6.33
+	Hs
		174745 SPTN2_HUMAN (1390-3107): 3.29e-22: 108: 12.11		ANK2_HUMAN (951-1283): 1.07e-22: 108: 5.52
+	Hs
		174752 SPTN2_HUMAN (1390-3107): 3.29e-22: 108: 12.11		ANK3_HUMAN (1158-1279): 2.77e-17: 90.9: 8.66
+	Hs
		1091457 SPTN4_HUMAN (1380-3073): 2.14e-16: 89.7: 11.41		ANK3_HUMAN (1158-1279): 2.77e-17: 90.9: 8.66