HitPredict

Interactor 1: ESYT2 (A0FGR8)
Extended synaptotagmin-2 (E-Syt2) (Chr2Syt)
Gene: ESYT2

Interactor 2: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C2~SNARE, C2~Syntaxin
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 921 Hs			1 297
+	Hs
		48444 ESYT2_HUMAN (1-921): 0: 839: 100.00		STX7_HUMAN (31-291): 4.49e-50: 167: 23.95
+	Mm
		204919 SYT2_MOUSE (262-496): 6.74e-29: 122: 17.03		STX1A_MOUSE (1-293): 8.06e-72: 224: 43.54
+	Dm
		638694 SY65_DROME (607-919): 1.53e-30: 128: 16.14		STX1A_DROME (2-293): 9e-68: 214: 38.91
+	Hs
		639106 SYT1_HUMAN (787-910): 3.16e-13: 74.7: 35.20		STX2_HUMAN (1-295): 4.49e-72: 225: 42.57
+	Rn
		639904 SYT1_RAT (787-910): 2.9e-13: 74.7: 35.20		STX1A_RAT (1-293): 1.02e-71: 224: 43.54
+	Hs
		746214 SYTL4_HUMAN (788-902): 3.44e-12: 72.4: 33.05		STX2_HUMAN (1-295): 4.49e-72: 225: 42.57
+	Hs
		639124 SYT1_HUMAN (787-910): 3.16e-13: 74.7: 35.20		STX4_HUMAN (1-297): 3.02e-70: 221: 100.00
+	Hs
		639135 SYT1_HUMAN (787-910): 3.16e-13: 74.7: 35.20		STX1A_HUMAN (1-293): 1.91e-70: 221: 43.20
+	Hs
		1087261 ESYT1_HUMAN (370-498): 3.85e-12: 72.7: 17.14		STX4_HUMAN (1-297): 3.02e-70: 221: 100.00
+	Hs
		1159617 SYTL4_HUMAN (788-902): 3.44e-12: 72.4: 33.05		STX1A_HUMAN (1-293): 1.91e-70: 221: 43.20
+	Hs
		639127 SYT1_HUMAN (787-910): 3.16e-13: 74.7: 35.20		STX3_HUMAN (1-295): 6.66e-57: 186: 38.31
+	Hs
		1100706 SYTL4_HUMAN (788-902): 3.44e-12: 72.4: 33.05		STX3_HUMAN (1-295): 6.66e-57: 186: 38.31
+	Hs
		189807 ESYT1_HUMAN (370-498): 3.85e-12: 72.7: 17.14		STX7_HUMAN (31-291): 4.49e-50: 167: 23.95