HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: UBE3A (Q05086)
Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)
Gene: UBE3A

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.698

The method score is based on:

Property Details
Experiments 36109631, 27903893, 16254014, 9891052
Identification Methods affinity chromatography technology, pull down, enzymatic study, biochemical
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0030521 - androgen receptor signaling pathway
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0060736 - prostate gland growth
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 920
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024