HitPredict

Interactor 1: BIP (P11021)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein) (GRP-78) (Binding-immunoglobulin protein) (BiP) (Heat shock protein 70 family protein 5) (HSP70 family protein 5) (Heat shock protein family A member 5) (Immunoglobulin heavy chain-binding protein)
Gene: HSPA5

Interactor 2: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 654 Hs			1 117
+	Hs
		713934 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00
+	Hs
		305992 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		503785 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00
+	Hs
		564050 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00
+	Hs
		714070 HS71L_HUMAN (24-647): 0: 922: 63.16		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		305925 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		305951 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		305924 BIP_HUMAN (19-654): 0: 914: 100.00		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		504734 HSP7C_HUMAN (26-637): 0: 916: 66.02		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		564180 HSP76_HUMAN (25-635): 0: 915: 62.54		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		502539 BIP_HUMAN (19-654): 0: 914: 100.00		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		714074 HS71L_HUMAN (24-647): 0: 922: 63.16		MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74
+	Hs
		714067 HS71L_HUMAN (24-647): 0: 922: 63.16		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Hs
		504756 HSP7C_HUMAN (26-637): 0: 916: 66.02		MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74
+	Hs
		564184 HSP76_HUMAN (25-635): 0: 915: 62.54		MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74
+	Hs
		502557 BIP_HUMAN (19-654): 0: 914: 100.00		MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74
+	Hs
		504720 HSP7C_HUMAN (26-637): 0: 916: 66.02		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Hs
		564178 HSP76_HUMAN (25-635): 0: 915: 62.54		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Hs
		502528 BIP_HUMAN (19-654): 0: 914: 100.00		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Hs
		483769 HS71A_HUMAN (26-635): 0: 911: 64.11		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14