HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	11909948, 14743216
Identification Methods	pull down, tandem affinity purification
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 455
+	Hs
		584330 HS71L_HUMAN (2-646): 0: 966: 82.48		TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00
+	Hs
		563998 HSP76_HUMAN (6-646): 0: 955: 77.54		TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00
+	Hs
		503419 HSP7C_HUMAN (1-646): 0: 967: 100.00		TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86
+	Hs
		591270 HS71L_HUMAN (2-646): 0: 966: 82.48		TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86
+	Hs
		503470 HSP7C_HUMAN (1-646): 0: 967: 100.00		TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64
+	Hs
		564001 HSP76_HUMAN (6-646): 0: 955: 77.54		TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86