HitPredict

Interactor 1: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	33961781, 36931259, 36736316, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1271 Hs			1 246
+	Hs
		506563 BCR_HUMAN (1-1271): 0: 1005: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		506568 BCR_HUMAN (1-1271): 0: 1005: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		506518 BCR_HUMAN (1-1271): 0: 1005: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Mm
		926818 BCR_MOUSE (1-1271): 0: 941: 93.79		1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02
+	Hs
		506562 BCR_HUMAN (1-1271): 0: 1005: 100.00		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		506573 BCR_HUMAN (1-1271): 0: 1005: 100.00		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		909717 FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683475 FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927201 FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909921 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683631 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927416 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		647028 FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		647196 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		904753 FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982180 FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		905000 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982392 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		684147 FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		684271 SPT13_HUMAN (264-860): 9.73e-89: 303: 15.25		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62