Protein: PIGT
GPI-anchor transamidase component PIGT (Phosphatidylinositol-glycan biosynthesis class T protein)

Gene: PIGT
Organism: Homo sapiens
Interactions: 230
UniProt ID: Q969N2

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0016020 - membrane
GO:0016255 - attachment of GPI anchor to protein
GO:0030182 - neuron differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1366353

GPI8
GPI-anchor transamidase

7

2

Small-scale

0.964

High

1380522

PIGS
GPI-anchor transamidase component PIGS

6

2

Small-scale

0.945

High

212595

GPAA1
GPI-anchor transamidase component GPAA1

5

1

Small-scale

0.931

High

1380533

PIGU
GPI-anchor transamidase component PIGU

3

0

High-throughput

0.811

High

1137917

TNIP1
TNFAIP3-interacting protein 1

3

1

High-throughput

0.604

High

1250499

RBP10
Ran-binding protein 10

3

2

High-throughput

0.604

High

1272712

MAEA
E3 ubiquitin-protein transferase MAEA

3

5

High-throughput

0.604

High

1380523

RANB9
Ran-binding protein 9

3

2

High-throughput

0.604

High

1380538

RMD5A
E3 ubiquitin-protein transferase RMND5A

3

4

High-throughput

0.604

High

1380546

GID8
Glucose-induced degradation protein 8 homolog

3

5

High-throughput

0.604

High

1380517

ZMY19
Zinc finger MYND domain-containing protein 19

2

0

High-throughput

0.602

High

242506

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

406979

THY1
Thy-1 membrane glycoprotein

2

0

High-throughput

0.576

High

1380519

RMD5B
E3 ubiquitin-protein transferase RMND5B

2

4

High-throughput

0.574

High

396663

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1380557

TSP50
Probable threonine protease PRSS50

2

1

High-throughput

0.558

High

248750

PEPL
Periplakin

1

1

High-throughput

0.536

High

333126

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.536

High

380467

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

1

High-throughput

0.536

High

652380

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

713428

SPB3
Serpin B3

1

4

High-throughput

0.536

High

945833

EPIPL
Epiplakin

1

2

High-throughput

0.536

High

1058571

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.536

High

1368991

EVPL
Envoplakin

1

2

High-throughput

0.536

High

1380545

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.536

High

1380556

CLC2D
C-type lectin domain family 2 member D

1

1

High-throughput

0.536

High

841065

HELZ
Probable helicase with zinc finger domain

2

0

High-throughput

0.528

High

1313781

S15A3
Solute carrier family 15 member 3

2

1

High-throughput

0.521

High

229058

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.513

High

276613

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

0

High-throughput

0.513

High

295754

AP1G2
AP-1 complex subunit gamma-like 2

1

0

High-throughput

0.513

High

390928

TRFE
Serotransferrin

1

0

High-throughput

0.513

High

483945

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.513

High

520956

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

690334

STOM
Stomatin

1

0

High-throughput

0.513

High

698982

CALX
Calnexin

1

0

High-throughput

0.513

High

1083521

BST2
Bone marrow stromal antigen 2

1

0

High-throughput

0.513

High

1105533

OS9
Protein OS-9

1

0

High-throughput

0.513

High

1128542

DSC3
Desmocollin-3

1

0

High-throughput

0.513

High

1159219

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

1200353

APRV1
Retroviral-like aspartic protease 1

1

0

High-throughput

0.513

High

1213664

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.513

High

1273265

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

1350028

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

1380513

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

1380514

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1380521

GSDMA
Gasdermin-A

1

0

High-throughput

0.513

High

1380528

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

0

High-throughput

0.513

High

1380530

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.513

High

1380536

SG196
Protein O-mannose kinase

1

0

High-throughput

0.513

High

1380539

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

1380568

A4GCT
Alpha-1,4-N-acetylglucosaminyltransferase

1

0

High-throughput

0.513

High

1380573

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.513

High

277767

H2AY
Core histone macro-H2A.1

1

1

High-throughput

0.489

High

289274

SPB7
Serpin B7

1

4

High-throughput

0.489

High

349520

TSN15
Tetraspanin-15

1

1

High-throughput

0.489

High

369902

CO3
Complement C3

1

3

High-throughput

0.489

High

387867

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

1

High-throughput

0.489

High

387997

FIBG
Fibrinogen gamma chain

1

1

High-throughput

0.489

High

424244

S10A8
Protein S100-A8

1

2

High-throughput

0.489

High

424534

PAI2
Plasminogen activator inhibitor 2

1

4

High-throughput

0.489

High

445042

S10A9
Protein S100-A9

1

4

High-throughput

0.489

High

462909

LAMB1
Laminin subunit beta-1

1

1

High-throughput

0.489

High

501844

CO4A
Complement C4-A

1

3

High-throughput

0.489

High

575687

GPIX
Platelet glycoprotein IX

1

1

High-throughput

0.489

High

577845

PLAK
Junction plakoglobin

1

1

High-throughput

0.489

High

615222

IL1RA
Interleukin-1 receptor antagonist protein

1

2

High-throughput

0.489

High

618406

TSN8
Tetraspanin-8

1

1

High-throughput

0.489

High

628438

KLK2
Kallikrein-2

1

4

High-throughput

0.489

High

706248

S10A2
Protein S100-A2

1

4

High-throughput

0.489

High

724613

S10A7
Protein S100-A7

1

4

High-throughput

0.489

High

868752

LEG7
Galectin-7

1

1

High-throughput

0.489

High

874836

SPB4
Serpin B4

1

4

High-throughput

0.489

High

892126

KLK7
Kallikrein-7

1

3

High-throughput

0.489

High

1062280

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.489

High

1256968

FBX50
F-box only protein 50

1

2

High-throughput

0.489

High

1286342

S1A7A
Protein S100-A7A

1

4

High-throughput

0.489

High

1363120

CLC2B
C-type lectin domain family 2 member B

1

1

High-throughput

0.489

High

1369669

KLK6
Kallikrein-6

1

4

High-throughput

0.489

High

1380532

KLK15
Kallikrein-15

1

4

High-throughput

0.489

High

1380549

IL36G
Interleukin-36 gamma

1

2

High-throughput

0.489

High

1380550

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.489

High

1380553

I36RA
Interleukin-36 receptor antagonist protein

1

2

High-throughput

0.489

High

1380561

SPB13
Serpin B13

1

4

High-throughput

0.489

High

1380563

FBX2
F-box only protein 2

1

2

High-throughput

0.489

High

1380571

PKP3
Plakophilin-3

1

1

High-throughput

0.489

High

404299

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

955450

CDC42
Cell division control protein 42 homolog

1

2

High-throughput

0.479

High

962353

RHOA
Transforming protein RhoA

1

1

High-throughput

0.479

High

1380552

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.479

High

315847

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

319955

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

412395

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

417652

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

951325

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

1205462

EMC4
ER membrane protein complex subunit 4

1

0

High-throughput

0.458

High

1252165

SYNE3
Nesprin-3

1

0

High-throughput

0.458

High

1290922

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

1351928

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.458

High

1380515

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1380520

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

104198

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.445

High

75704

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

3

High-throughput

0.437

High

125562

LEG9
Galectin-9

1

1

High-throughput

0.437

High

218589

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

566785

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.437

High

1380534

RHOJ
Rho-related GTP-binding protein RhoJ

1

2

High-throughput

0.437

High

1380541

FBX6
F-box only protein 6

1

2

High-throughput

0.437

High

256106

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

287989

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.426

High

351241

MOT3
Monocarboxylate transporter 3

1

0

High-throughput

0.426

High

869641

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

0

High-throughput

0.426

High

1047329

P
P protein

1

0

High-throughput

0.426

High

1113923

CUL3
Cullin-3

1

0

High-throughput

0.426

High

1139527

S39AE
Metal cation symporter ZIP14

1

0

High-throughput

0.426

High

1162148

MA2A1
Alpha-mannosidase 2

1

0

High-throughput

0.426

High

1209481

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1236258

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1242190

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.426

High

1336025

CTL5
Choline transporter-like protein 5

1

0

High-throughput

0.426

High

1337896

ZNT7
Zinc transporter 7

1

0

High-throughput

0.426

High

1380527

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

0

High-throughput

0.426

High

1380565

CCPG1
Cell cycle progression protein 1

1

0

High-throughput

0.426

High

1380570

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

0

High-throughput

0.426

High

69527

A2ML1
Alpha-2-macroglobulin-like protein 1

1

3

High-throughput

0.407

High

303265

S22A5
Organic cation/carnitine transporter 2

1

1

High-throughput

0.407

High

379124

IGKC
Immunoglobulin kappa constant

1

6

High-throughput

0.407

High

379289

IGHG1
Immunoglobulin heavy constant gamma 1

1

6

High-throughput

0.407

High

379379

IGHG2
Immunoglobulin heavy constant gamma 2

1

6

High-throughput

0.407

High

379436

IGHG3
Immunoglobulin heavy constant gamma 3

1

6

High-throughput

0.407

High

379468

IGHG4
Immunoglobulin heavy constant gamma 4

1

6

High-throughput

0.407

High

379692

IGHA1
Immunoglobulin heavy constant alpha 1

1

6

High-throughput

0.407

High

506525

IGLC6
Immunoglobulin lambda constant 6

1

6

High-throughput

0.407

High

1117035

LAMC2
Laminin subunit gamma-2

1

1

High-throughput

0.407

High

1308926

S22A9
Organic anion transporter 7

1

1

High-throughput

0.407

High

1333183

AFG2A
ATPase family gene 2 protein homolog A

1

1

High-throughput

0.407

High

1258157

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

3

0

High-throughput

0.345

High

1380516

F136A
Protein FAM136A

3

0

High-throughput

0.345

High

1380537

WDR26
WD repeat-containing protein 26

3

0

High-throughput

0.345

High

1380564

MKLN1
Muskelin

3

0

High-throughput

0.345

High

725154

HXC9
Homeobox protein Hox-C9

2

0

High-throughput

0.328

High

1211517

CE85L
Centrosomal protein of 85 kDa-like

2

0

High-throughput

0.328

High

1230794

ANR40
Ankyrin repeat domain-containing protein 40

2

0

High-throughput

0.328

High

1244409

BORA
Protein aurora borealis

2

0

High-throughput

0.328

High

1307888

ARMC8
Armadillo repeat-containing protein 8

2

0

High-throughput

0.328

High

1309296

GID4
Glucose-induced degradation protein 4 homolog

2

0

High-throughput

0.328

High

1333648

PGLT1
Protein O-glucosyltransferase 1

2

0

High-throughput

0.328

High

1368815

N42L2
NEDD4-binding protein 2-like 2

2

0

High-throughput

0.328

High

1380555

EGFL7
Epidermal growth factor-like protein 7

2

0

High-throughput

0.328

High

174386

ZN609
Zinc finger protein 609

2

0

High-throughput

0.313

High

126245

ST2B1
Sulfotransferase 2B1

1

0

High-throughput

0.279

Low

183360

ZN185
Zinc finger protein 185

1

0

High-throughput

0.279

Low

219344

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.279

Low

238672

AK1BA
Aldo-keto reductase family 1 member B10

1

0

High-throughput

0.279

Low

332689

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.279

Low

370347

CYTA
Cystatin-A

1

0

High-throughput

0.279

Low

423688

ARGI1
Arginase-1

1

0

High-throughput

0.279

Low

457896

INVO
Involucrin

1

0

High-throughput

0.279

Low

506889

CFC1
Cryptic protein

1

0

High-throughput

0.279

Low

567944

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.279

Low

568275

PLST
Plastin-3

1

0

High-throughput

0.279

Low

578695

GLNA
Glutamine synthetase

1

0

High-throughput

0.279

Low

595546

H15
Histone H1.5

1

0

High-throughput

0.279

Low

609318

SAP3
Ganglioside GM2 activator

1

0

High-throughput

0.279

Low

627144

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.279

Low

631393

RAB5A
Ras-related protein Rab-5A

1

0

High-throughput

0.279

Low

636178

ENDOU
Uridylate-specific endoribonuclease

1

0

High-throughput

0.279

Low

636878

GSTM3
Glutathione S-transferase Mu 3

1

0

High-throughput

0.279

Low

692768

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

722802

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

High-throughput

0.279

Low

730815

1433S
14-3-3 protein sigma

1

0

High-throughput

0.279

Low

827880

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.279

Low

839605

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

1031119

HMCS1
Hydroxymethylglutaryl-CoA synthase, cytoplasmic

1

0

High-throughput

0.279

Low

1057106

FMOD
Fibromodulin

1

0

High-throughput

0.279

Low

1065889

MB214
Protein mab-21-like 4

1

0

High-throughput

0.279

Low

1120943

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

1142128

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1187258

PA24E
Cytosolic phospholipase A2 epsilon

1

0

High-throughput

0.279

Low

1206872

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.279

Low

1211826

AXDN1
Axonemal dynein light chain domain-containing protein 1

1

0

High-throughput

0.279

Low

1248719

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

1273103

EEPD1
Endonuclease/exonuclease/phosphatase family domain-containing protein 1

1

0

High-throughput

0.279

Low

1307291

H2A2B
Histone H2A type 2-B

1

0

High-throughput

0.279

Low

1310287

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1338056

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

1358539

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

1366159

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.279

Low

1380518

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.279

Low

1380525

TREX2
Three prime repair exonuclease 2

1

0

High-throughput

0.279

Low

1380540

TIGAR
Fructose-2,6-bisphosphatase TIGAR

1

0

High-throughput

0.279

Low

1380554

ZO2
Tight junction protein 2

1

0

High-throughput

0.279

Low

1380558

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.279

Low

1380560

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.279

Low

1380562

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.279

Low

1380566

ASC
Apoptosis-associated speck-like protein containing a CARD

1

0

High-throughput

0.279

Low

1380567

NDRG2
Protein NDRG2

1

0

High-throughput

0.279

Low

1380572

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

0

High-throughput

0.279

Low

124636

EYA2
Protein phosphatase EYA2

1

0

High-throughput

0.249

Low

589339

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696134

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

901461

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.249

Low

1004930

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1162463

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1229609

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

1238764

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

1254938

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1312570

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1380524

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.249

Low

1380535

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1380543

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

1380544

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1380548

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

1380559

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

1380531

REN3A
Regulator of nonsense transcripts 3A

1

0

High-throughput

0.238

Low

222313

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low

253716

SRPX2
Sushi repeat-containing protein SRPX2

1

0

High-throughput

0.232

Low

756578

GALNS
N-acetylgalactosamine-6-sulfatase

1

0

High-throughput

0.232

Low

977142

YPEL5
Protein yippee-like 5

1

0

High-throughput

0.232

Low

1216232

H37
Histone H3-7

1

0

High-throughput

0.232

Low

1217674

AXA81
Annexin A8-like protein 1

1

0

High-throughput

0.232

Low

1246098

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

0

High-throughput

0.232

Low

1250383

PCD23
Protocadherin-23

1

0

High-throughput

0.232

Low

1363780

YLAT2
Y+L amino acid transporter 2

1

0

High-throughput

0.232

Low

1380526

SYTM
Threonine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low

1380529

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

0

High-throughput

0.232

Low

1380542

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

1

0

High-throughput

0.232

Low

1380547

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

0

High-throughput

0.232

Low

1380551

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.232

Low

1380569

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025