HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PSA3 (P25788)
Proteasome subunit alpha type-3 (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8) (Proteasome subunit alpha-7) (alpha-7)
Gene: PSMA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16196087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 255
+	Hs
		507560 UBC_HUMAN (1-685): 0: 857: 100.00		PSA5_HUMAN (1-239): 1.18e-96: 284: 31.97
+	Hs
		507750 UBC_HUMAN (1-685): 0: 857: 100.00		PSA6_HUMAN (4-242): 5.9e-96: 283: 29.34
+	Hs
		165242 UBC_HUMAN (1-685): 0: 857: 100.00		PSA7_HUMAN (7-237): 1.54e-93: 277: 31.76
+	Rn
		954937 UBC_RAT (1-637): 0: 779: 98.90		PSA6_RAT (4-242): 5.9e-96: 283: 29.34
+	At
		307138 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		PSA4A_ARATH (4-249): 3.17e-100: 293: 32.80
+	At
		200661 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		PSA3_ARATH (1-250): 1.09e-96: 285: 60.40
+	At
		307131 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		PSA6A_ARATH (4-242): 5.36e-95: 280: 33.47
+	At
		201186 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		PSA7B_ARATH (6-236): 9.11e-94: 277: 28.45
+	Sc
		509409 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		PSA3_YEAST (8-198): 2.63e-34: 125: 35.42
+	Hs
		681326 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		PSA3_HUMAN (1-255): 1.86e-97: 287: 100.00
+	Hs
		954784 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		PSA6_HUMAN (4-242): 5.9e-96: 283: 29.34
+	Hs
		681619 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		PSA4_HUMAN (4-236): 1.73e-94: 279: 27.43
+	At
		307134 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		PSA6B_ARATH (5-184): 8.94e-35: 126: 40.88
+	Hs
		181971 UBD_HUMAN (155-304): 7.59e-28: 112: 32.05		PSA3_HUMAN (1-255): 1.86e-97: 287: 100.00
+	Hs
		181973 UBD_HUMAN (155-304): 7.59e-28: 112: 32.05		PSA5_HUMAN (1-239): 1.18e-96: 284: 31.97
+	Hs
		181984 UBD_HUMAN (155-304): 7.59e-28: 112: 32.05		PSA6_HUMAN (4-242): 5.9e-96: 283: 29.34
+	Hs
		181972 UBD_HUMAN (155-304): 7.59e-28: 112: 32.05		PSA4_HUMAN (4-236): 1.73e-94: 279: 27.43
+	Hs
		165204 UBD_HUMAN (155-304): 7.59e-28: 112: 32.05		PSA7_HUMAN (7-237): 1.54e-93: 277: 31.76
+	Hs
		507088 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		PSA4_HUMAN (4-236): 1.73e-94: 279: 27.43