HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UB2G1 (P62253)
Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]
Gene: UBE2G1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	27182664, 34642328
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 170
+	Hs
		508868 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D4_HUMAN (5-165): 1.39e-72: 216: 34.16
+	Hs
		507701 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D1_HUMAN (5-165): 3.33e-72: 215: 34.78
+	Hs
		507678 UBC_HUMAN (1-685): 0: 857: 100.00		UB2R1_HUMAN (1-163): 1.96e-70: 214: 51.83
+	Hs
		507793 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D2_HUMAN (5-165): 7.65e-72: 214: 32.92
+	Hs
		507755 UBC_HUMAN (1-685): 0: 857: 100.00		UB2D3_HUMAN (5-165): 2.84e-70: 210: 32.92
+	Hs
		508183 UBC_HUMAN (1-685): 0: 857: 100.00		UB2R2_HUMAN (1-163): 2.31e-68: 209: 54.27
+	Hs
		507746 UBC_HUMAN (1-685): 0: 857: 100.00		UB2G2_HUMAN (1-164): 5.29e-67: 203: 50.00
+	Rn
		92896 UBC_RAT (1-637): 0: 779: 98.90		UB2D1_RAT (5-165): 3.33e-72: 215: 34.78
+	Xl
		982387 Q7SY79_XENLA (77-685): 0: 752: 99.84		UB2D2_XENLA (5-165): 7.65e-72: 214: 32.92
+	Dm
		683066 Q9W418_DROME (229-685): 0: 567: 99.78		UBCD1_DROME (5-165): 3.04e-71: 213: 34.16
+	Sc
		509374 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC4_YEAST (4-165): 3.47e-71: 213: 33.33
+	Sc
		509687 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC7_YEAST (3-164): 5.84e-67: 203: 49.38
+	Sc
		509369 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBC3_YEAST (9-166): 7.32e-36: 127: 41.62
+	At
		762746 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC8_ARATH (5-165): 3.76e-72: 215: 31.68
+	At
		762762 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC9_ARATH (5-165): 1.84e-71: 213: 31.68
+	At
		762777 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC10_ARATH (5-165): 1.65e-71: 213: 31.06
+	At
		762787 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC11_ARATH (5-165): 1.53e-71: 213: 32.30
+	At
		842112 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC14_ARATH (1-168): 7.76e-67: 202: 58.93
+	At
		683037 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC1_ARATH (10-164): 8.3e-31: 110: 36.77
+	At
		842109 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBC2_ARATH (10-164): 7.62e-31: 110: 36.77