HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: BIRC7 (Q96CA5)
Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]
Gene: BIRC7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22902369
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4_3
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 298
+	Hs
		508684 UBC_HUMAN (1-685): 0: 857: 100.00		BIRC6_HUMAN (54-252): 7.19e-36: 138: 21.10
+	Hs
		508397 UBC_HUMAN (1-685): 0: 857: 100.00		MIB2_HUMAN (236-297): 7.75e-23: 100: 38.71
+	Hs
		507930 UBC_HUMAN (1-685): 0: 857: 100.00		BIRC3_HUMAN (238-298): 4.64e-20: 92: 70.97
+	Hs
		508238 UBC_HUMAN (1-685): 0: 857: 100.00		MIB1_HUMAN (206-296): 7.32e-20: 91.6: 25.28
+	Hs
		507931 UBC_HUMAN (1-685): 0: 857: 100.00		BIRC2_HUMAN (84-281): 5.34e-19: 88.9: 23.23
+	Hs
		507839 UBC_HUMAN (1-685): 0: 857: 100.00		XIAP_HUMAN (1-96): 3.49e-13: 71.6: 19.19
+	Rn
		1224550 UBC_RAT (1-637): 0: 779: 98.90		XIAP_RAT (1-96): 1.1e-11: 66.9: 16.16
+	Xl
		1232880 Q7SY79_XENLA (77-685): 0: 752: 99.84		MIB1_XENLA (206-296): 8.52e-20: 91.6: 27.47
+	Dr
		47846 Q6IS68_DANRE (222-685): 0: 569: 98.49		A0AR23_DANRE (237-297): 1.37e-21: 96.8: 36.07
+	Dr
		47837 F1QHN6_DANRE (229-685): 0: 566: 99.78		A0AR23_DANRE (237-297): 1.37e-21: 96.8: 36.07
+	Dr
		47847 Q7SXA3_DANRE (609-684): 5.02e-41: 148: 100.00		A0AR23_DANRE (237-297): 1.37e-21: 96.8: 36.07
+	Mm
		509194 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		MIB2_MOUSE (212-297): 1.17e-22: 99: 30.23
+	Hs
		181961 UBD_HUMAN (155-304): 7.59e-28: 112: 32.05		BIRC5_HUMAN (78-162): 9.66e-30: 111: 32.22
+	Mm
		148434 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		BIRC3_MOUSE (238-298): 1.91e-19: 90: 67.74
+	Hs
		507188 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		BIRC3_HUMAN (238-298): 4.64e-20: 92: 70.97
+	Mm
		509093 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		XIAP_MOUSE (1-96): 2.28e-12: 68.9: 18.18
+	Hs
		507160 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		XIAP_HUMAN (1-96): 3.49e-13: 71.6: 19.19