HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016477 - cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 870
+	Hs
		601488 FGFR2_HUMAN (1-821): 0: 803: 71.21		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		609231 FGFR3_HUMAN (6-821): 0: 730: 61.22		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		601499 FGFR2_HUMAN (1-821): 0: 803: 71.21		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		607932 FGFR4_HUMAN (29-808): 0: 664: 55.60		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		507961 FGFR1_HUMAN (1-822): 0: 861: 100.00		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		302247 FGFR1_HUMAN (1-822): 0: 861: 100.00		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		508140 FGFR1_HUMAN (1-822): 0: 861: 100.00		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Hs
		203204 FGFR1_HUMAN (1-822): 0: 861: 100.00		SYNJ1_HUMAN (281-696): 4.9e-10: 65.7: 13.47
+	Hs
		665392 EPHA3_HUMAN (3-775): 0: 643: 19.03		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		297957 FGFR3_HUMAN (6-821): 0: 730: 61.22		FCSD2_HUMAN (3-156): 3.32e-24: 110: 24.68
+	Hs
		665216 EPHA2_HUMAN (3-819): 0: 583: 18.68		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		302255 FGFR4_HUMAN (29-808): 0: 664: 55.60		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		974084 NTRK2_HUMAN (102-762): 5.62e-163: 495: 22.70		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		665643 EPHB2_HUMAN (4-819): 0: 640: 18.07		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Hs
		302258 EPHA8_HUMAN (3-819): 0: 603: 19.35		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		992580 NTRK2_HUMAN (102-762): 5.62e-163: 495: 22.70		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		992578 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		674405 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		302291 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		257545 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		ANR17_HUMAN (67-718): 5.11e-09: 62.6: 9.52