HitPredict

Interactor 1: TOP1 (P11387)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I)
Gene: TOP1

Interactor 2: GRWD1 (Q9BQ67)
Glutamate-rich WD repeat-containing protein 1
Gene: GRWD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	29991511, 12549820
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005694 - chromosome and 2 others more... GO:0005730 - nucleolus GO:0006260 - DNA replication
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 765 Hs			1 446
+	Hs
		508477 TOP1_HUMAN (1-765): 0: 932: 100.00		RBBP4_HUMAN (62-247): 7.65e-20: 93.1: 10.71