HitPredict

Interactor 1: UBI4P (P0CG63)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBI4

Interactor 2: UBA3 (Q99344)
NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.64) (RUB1-activating enzyme E1) (Ubiquitin-activating enzyme E1 3) (Ubiquitin-like protein-activating enzyme)
Gene: UBA3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	38803224
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 381 Sc			1 299
+	Rn
		1224501 UBC_RAT (1-333): 1.4e-131: 397: 93.99		UBA3_RAT (3-299): 7.88e-114: 338: 41.61
+	Sc
		509542 UBI4P_YEAST (1-381): 3.26e-162: 461: 100.00		UBA4_YEAST (2-161): 4.22e-48: 167: 29.01
+	Sc
		509404 UBI4P_YEAST (1-381): 3.26e-162: 461: 100.00		UBA1_YEAST (3-144): 4.59e-21: 95.1: 23.78
+	Mm
		509039 UBC_MOUSE (1-333): 1.47e-132: 398: 93.99		UBA1_MOUSE (3-143): 1.16e-24: 105: 24.82
+	Rn
		1216901 UBC_RAT (1-333): 1.4e-131: 397: 93.99		UBA1_RAT (3-143): 1.07e-23: 103: 24.82
+	Mm
		509171 UBC_MOUSE (1-333): 1.47e-132: 398: 93.99		UBA6_MOUSE (2-143): 3.6e-18: 86.7: 20.00
+	At
		1020535 UBQ3_ARATH (77-381): 2.5e-126: 367: 97.05		UBE11_ARATH (3-227): 5.12e-20: 92.1: 20.89
+	Hs
		508765 UBC_HUMAN (1-153): 1.3e-50: 181: 95.43		SAE2_HUMAN (4-263): 4.77e-74: 240: 31.56
+	Hs
		182006 UBD_HUMAN (231-380): 1.49e-30: 116: 30.77		SAE2_HUMAN (4-263): 4.77e-74: 240: 31.56
+	Hs
		182004 UBD_HUMAN (231-380): 1.49e-30: 116: 30.77		SAE1_HUMAN (3-276): 3.2e-73: 230: 15.11
+	Hs
		507527 UBC_HUMAN (1-153): 1.3e-50: 181: 95.43		UBA1_HUMAN (3-143): 9.46e-24: 103: 24.82
+	Hs
		48331 UBC_HUMAN (1-153): 1.3e-50: 181: 95.43		UBA6_HUMAN (2-143): 1.92e-20: 93.6: 19.31
+	Sc
		436321 RS31_YEAST (305-380): 1.89e-41: 144: 100.00		UBA1_YEAST (3-144): 4.59e-21: 95.1: 23.78
+	Hs
		181968 UBD_HUMAN (231-380): 1.49e-30: 116: 30.77		UBA1_HUMAN (3-143): 9.46e-24: 103: 24.82
+	Hs
		425356 ISG15_HUMAN (3-152): 9.49e-31: 117: 32.68		UBA7_HUMAN (3-141): 1.22e-20: 94: 23.74
+	Hs
		48320 UBD_HUMAN (231-380): 1.49e-30: 116: 30.77		UBA6_HUMAN (2-143): 1.92e-20: 93.6: 19.31
+	Hs
		647534 RS27A_HUMAN (77-153): 6.09e-20: 87.4: 94.81		UBA1_HUMAN (3-143): 9.46e-24: 103: 24.82