Protein: UBA1
Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Ubiquitin-activating enzyme E1) (Ubiquitin-activating enzyme E1 X) (Ubiquitin-like modifier-activating enzyme 1 X)

Gene: UBA1
Organism: Mus musculus
Interactions: 26
UniProt ID: Q02053

Gene Ontology (top 5):
GO:0000792 - heterochromatin
GO:0004839 - ubiquitin activating enzyme activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509039

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

14

High-throughput

0.647

High

1034645

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

3

0

High-throughput

0.622

High

1034647

DLG4
Disks large homolog 4

3

0

High-throughput

0.622

High

1034650

NEB2
Neurabin-2

2

2

High-throughput

0.584

High

1034652

MYOME
Myomegalin

1

1

High-throughput

0.536

High

1034656

EED
Polycomb protein EED

1

4

High-throughput

0.515

High

236575

ITB3
Integrin beta-3

1

2

High-throughput

0.501

High

543025

CDK1
Cyclin-dependent kinase 1

1

2

Small-scale

0.501

High

147772

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.479

High

530795

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.479

High

555190

FABPL
Fatty acid-binding protein, liver

1

1

Small-scale

0.479

High

1034644

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

4

High-throughput

0.479

High

1034646

PPP5
Serine/threonine-protein phosphatase 5

1

3

High-throughput

0.479

High

1034649

TFE3
Transcription factor E3

1

1

High-throughput

0.479

High

1034651

FACD2
Fanconi anemia group D2 protein homolog

1

4

High-throughput

0.479

High

1034654

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1034657

ATAD1
Outer mitochondrial transmembrane helix translocase

1

6

Small-scale

0.479

High

1034658

SPAST
Spastin

1

5

High-throughput

0.479

High

927736

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

1034648

RO52
E3 ubiquitin-protein ligase TRIM21

1

2

Small-scale

0.445

High

595173

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.437

High

906630

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

1

High-throughput

0.437

High

1034655

MT21E
Protein-lysine methyltransferase METTL21E

1

2

High-throughput

0.437

High

915547

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.426

High

551420

A4
Amyloid-beta precursor protein

1

5

Small-scale

0.408

High

1034653

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025