Interactor 1: GLI3 (P10071)
Transcriptional activator GLI3 (GLI3 form of 190 kDa) (GLI3-190) (GLI3 full-length protein) (GLI3FL) [Cleaved into: Transcriptional repressor GLI3R (GLI3 C-terminally truncated form) (GLI3 form of 83 kDa) (GLI3-83)]
Gene: GLI3
Interactor 2: SUFU (Q9UMX1)
Suppressor of fused homolog (SUFUH)
Gene: SUFU
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.81 | 0.60 | 0.697 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29515120, 10564661, 35140242, 24311597 |
| Identification Methods | protein complementation assay, pull down, proximity labelling technology, affinity chromatography technology, x-ray crystallography, mass spectrometry study of hydrogen/deuterium exchange |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 9 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
