Protein: ZIC1
Zinc finger protein ZIC 1 (Zinc finger protein 201) (Zinc finger protein of the cerebellum 1)

Gene: ZIC1
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q15915

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

217095

MS18B
Protein Mis18-beta

2

1

High-throughput

0.783

High

1156023

ZN620
Zinc finger protein 620

2

19

High-throughput

0.783

High

1156058

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

2

18

High-throughput

0.783

High

466671

GLI1
Zinc finger protein GLI1

1

18

Small-scale

0.724

High

517476

GLI2
Zinc finger protein GLI2

1

19

Small-scale

0.724

High

517533

GLI3
Transcriptional activator GLI3

1

18

Small-scale

0.724

High

369460

AACT
Alpha-1-antichymotrypsin

2

7

High-throughput

0.628

High

423779

APOD
Apolipoprotein D

2

1

High-throughput

0.628

High

444989

S10A9
Protein S100-A9

2

7

High-throughput

0.628

High

671799

ZA2G
Zinc-alpha-2-glycoprotein

2

1

High-throughput

0.628

High

682494

S100P
Protein S100-P

2

7

High-throughput

0.628

High

713387

SPB3
Serpin B3

2

7

High-throughput

0.628

High

724578

S10A7
Protein S100-A7

2

7

High-throughput

0.628

High

729565

CASPE
Caspase-14

2

1

High-throughput

0.628

High

1156017

KPRP
Keratinocyte proline-rich protein

2

1

High-throughput

0.628

High

1156024

FBX50
F-box only protein 50

2

1

High-throughput

0.628

High

1156036

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

2

1

High-throughput

0.628

High

1156044

S10AG
Protein S100-A16

2

7

High-throughput

0.628

High

1156066

CBPA4
Carboxypeptidase A4

2

1

High-throughput

0.628

High

1156067

SPB13
Serpin B13

2

7

High-throughput

0.628

High

1156034

ZNF34
Zinc finger protein 34

1

12

High-throughput

0.621

High

210005

CRX
Cone-rod homeobox protein

2

15

High-throughput

0.606

High

256531

TBX19
T-box transcription factor TBX19

2

6

High-throughput

0.606

High

288093

FOXH1
Forkhead box protein H1

2

8

High-throughput

0.606

High

769865

RFC2
Replication factor C subunit 2

2

1

High-throughput

0.606

High

1044639

ARI5A
AT-rich interactive domain-containing protein 5A

2

3

High-throughput

0.606

High

1048862

REL
Proto-oncogene c-Rel

2

4

High-throughput

0.606

High

1061711

TLE5
TLE family member 5

2

5

High-throughput

0.606

High

1093826

TRAF1
TNF receptor-associated factor 1

2

10

High-throughput

0.606

High

1106551

SMAD4
Mothers against decapentaplegic homolog 4

2

11

High-throughput

0.606

High

1151515

TRIP6
Thyroid receptor-interacting protein 6

2

4

High-throughput

0.606

High

1156038

IKBD
NF-kappa-B inhibitor delta

2

6

High-throughput

0.606

High

1156041

RBPMS
RNA-binding protein with multiple splicing

2

3

High-throughput

0.606

High

1156042

EFMT3
EEF1A lysine methyltransferase 3

2

2

High-throughput

0.606

High

1156046

AP4AT
AP-4 complex accessory subunit Tepsin

2

1

High-throughput

0.606

High

1156048

BBS4
BBSome complex member BBS4

2

3

High-throughput

0.606

High

1156050

SPAG8
Sperm-associated antigen 8

2

1

High-throughput

0.606

High

1156051

RUSC1
AP-4 complex accessory subunit RUSC1

2

1

High-throughput

0.606

High

1156062

PLS3
Phospholipid scramblase 3

2

2

High-throughput

0.606

High

1156063

ANR10
Ankyrin repeat domain-containing protein 10

2

7

High-throughput

0.606

High

1156064

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.606

High

1156065

PEF1
Peflin

2

3

High-throughput

0.606

High

1156069

SUFU
Suppressor of fused homolog

2

11

High-throughput

0.606

High

1156070

MAGD1
Melanoma-associated antigen D1

2

7

High-throughput

0.606

High

370306

CYTA
Cystatin-A

2

0

High-throughput

0.602

High

423659

ARGI1
Arginase-1

2

0

High-throughput

0.602

High

457867

INVO
Involucrin

2

0

High-throughput

0.602

High

582574

PPAP
Prostatic acid phosphatase

2

0

High-throughput

0.602

High

1156001

ECM1
Extracellular matrix protein 1

2

0

High-throughput

0.602

High

1156054

RNAS7
Ribonuclease 7

2

0

High-throughput

0.602

High

49487

DAPL1
Death-associated protein-like 1

2

0

High-throughput

0.580

High

1156016

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

2

0

High-throughput

0.580

High

1156018

INT11
Integrator complex subunit 11

2

0

High-throughput

0.580

High

1156022

ZN474
Zinc finger protein 474

2

0

High-throughput

0.580

High

1156049

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

0

High-throughput

0.580

High

1156056

CFA68
Cilia- and flagella-associated protein 68

2

0

High-throughput

0.580

High

261624

CATL2
Cathepsin L2

2

1

High-throughput

0.574

High

276588

LX12B
Arachidonate 12-lipoxygenase, 12R-type

2

2

High-throughput

0.574

High

485794

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

2

1

High-throughput

0.574

High

652321

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

1

High-throughput

0.574

High

721508

ILEU
Leukocyte elastase inhibitor

2

7

High-throughput

0.574

High

874789

SPB4
Serpin B4

2

7

High-throughput

0.574

High

1156045

CPNS2
Calpain small subunit 2

2

3

High-throughput

0.574

High

1156047

GSDMA
Gasdermin-A

2

2

High-throughput

0.574

High

1156052

LOXE3
Hydroperoxide isomerase ALOXE3

2

2

High-throughput

0.574

High

959471

YPEL3
Protein yippee-like 3

1

1

High-throughput

0.555

High

50334

F168B
Myelin-associated neurite-outgrowth inhibitor

2

1

High-throughput

0.553

High

70218

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.553

High

300362

KRT34
Keratin, type I cuticular Ha4

2

14

High-throughput

0.553

High

948270

KR121
Keratin-associated protein 12-1

2

2

High-throughput

0.553

High

950487

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.553

High

1145950

K1H1
Keratin, type I cuticular Ha1

2

14

High-throughput

0.553

High

1156004

KRA61
Keratin-associated protein 6-1

2

2

High-throughput

0.553

High

1156005

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.553

High

1156007

KR195
Keratin-associated protein 19-5

2

1

High-throughput

0.553

High

1156008

KR151
Keratin-associated protein 15-1

2

1

High-throughput

0.553

High

1156011

KR197
Keratin-associated protein 19-7

2

1

High-throughput

0.553

High

1156014

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.553

High

1156015

KLH26
Kelch-like protein 26

2

3

High-throughput

0.553

High

1156032

KRA81
Keratin-associated protein 8-1

2

2

High-throughput

0.553

High

1156037

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

2

1

High-throughput

0.553

High

1156039

OXER1
Oxoeicosanoid receptor 1

2

1

High-throughput

0.553

High

408898

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

High-throughput

0.536

High

457097

CAN1
Calpain-1 catalytic subunit

1

3

High-throughput

0.536

High

577773

PLAK
Junction plakoglobin

1

9

High-throughput

0.536

High

895441

SPB8
Serpin B8

1

7

High-throughput

0.536

High

1156043

DDT4L
DNA damage-inducible transcript 4-like protein

1

2

High-throughput

0.515

High

1156055

GO45
Golgin-45

1

2

High-throughput

0.515

High

1156057

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

3

High-throughput

0.515

High

1156061

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

1

3

High-throughput

0.515

High

161874

IMPA2
Inositol monophosphatase 2

1

0

High-throughput

0.513

High

1108785

ASAH1
Acid ceramidase

1

0

High-throughput

0.513

High

1156029

GA2L3
GAS2-like protein 3

1

0

High-throughput

0.493

High

1156060

PLAT1
Phospholipase A and acyltransferase 1

1

0

High-throughput

0.493

High

1156068

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.493

High

1009652

NGAL
Neutrophil gelatinase-associated lipocalin

1

1

High-throughput

0.489

High

1156059

S10AE
Protein S100-A14

1

7

High-throughput

0.489

High

993589

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.481

High

1156027

R144B
E3 ubiquitin-protein ligase RNF144B

1

13

High-throughput

0.481

High

1156040

TSC1
Hamartin

1

9

High-throughput

0.481

High

1156006

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.470

High

1156025

Q7KZS0
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.470

High

1156028

Q86WV8
TSC complex subunit 1

1

3

High-throughput

0.470

High

609310

SAP3
Ganglioside GM2 activator

2

0

High-throughput

0.328

High

839558

HUTH
Histidine ammonia-lyase

2

0

High-throughput

0.328

High

1156010

PA24E
Cytosolic phospholipase A2 epsilon

2

0

High-throughput

0.328

High

1156021

PLBL1
Phospholipase B-like 1

2

0

High-throughput

0.328

High

1156026

GDPD3
Lysophospholipase D GDPD3

2

0

High-throughput

0.328

High

1156002

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

1156003

KR212
Keratin-associated protein 21-2

2

0

High-throughput

0.316

High

1156013

SPAS1
Spermatogenesis-associated serine-rich protein 1

2

0

High-throughput

0.316

High

1156019

UFSP1
Ufm1-specific protease 1

2

0

High-throughput

0.316

High

1156020

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

2

0

High-throughput

0.316

High

1156030

KR191
Keratin-associated protein 19-1

2

0

High-throughput

0.316

High

1156031

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

1156033

KRA71
Keratin-associated protein 7-1

2

0

High-throughput

0.316

High

1156035

MET27
Methyltransferase-like protein 27

2

0

High-throughput

0.316

High

1156053

KRA32
Keratin-associated protein 3-2

2

0

High-throughput

0.316

High

1156071

ATP23
Mitochondrial inner membrane protease ATP23 homolog

2

0

High-throughput

0.316

High

892106

KLK7
Kallikrein-7

1

0

High-throughput

0.279

Low

1156009

KR221
Keratin-associated protein 22-1

1

0

High-throughput

0.251

Low

1156012

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025